Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788200 | 0.76 | ADRB2 (0.47) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL4740762 | 0.74 | ADRB2 (0.52) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL3589761 | 0.74 | ADRB2 (0.45) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Acetic Acid SCHEMBL4742751 | 0.73 | ADRB2 (0.47) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Bromide SCHEMBL1683003 | 0.73 | ADRB2 (0.51) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL1179939 | 0.73 | ADRB2 (0.51) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL3685863 | 0.72 | ADRB2 (0.40) | ADRB2ADRB1 | |
| SCHEMBL1683034 | 0.71 | ADRB2 (0.59) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL14291843 | 0.71 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL2815909 | 0.70 | ADRB2 (0.50) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709511-B2 | Benzothiazolone derivatives | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20080300275-A1 | Novel Benzothiazolone Derivatives | ASTRAZENECA AB (SE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300275-A1 | Novel Benzothiazolone Derivatives | NR0B1, RB1, CCND1 | ADRB2 156/4885ABCB11 487/4885ADRB1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.