SCHEMBL3590827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4670178	0.90	ALDH1A1 (0.47)	PPARDALDH1A1MAPTLMNAHTT
	SCHEMBL3590071	0.90	NPSR1 (0.53)	PPARDALDH1A1MAPTLMNANPSR1
	SCHEMBL3581683	0.84	PPARD (0.56)	PPARDALDH1A1MAPTLMNANPSR1
	SCHEMBL3597401	0.80	NPSR1 (0.55)	ALDH1A1MAPTLMNAHTTNPSR1
	SCHEMBL3593253	0.79	NPSR1 (0.59)	ALDH1A1MAPTLMNANPSR1HPGD
	SCHEMBL3589035	0.79	NPSR1 (0.67)	PPARDALDH1A1MAPTLMNAHTT
	SCHEMBL3589805	0.78	GFER (0.53)	PPARDALDH1A1MAPTLMNAHTT
	SCHEMBL3595381	0.78	NPSR1 (0.56)	ALDH1A1MAPTLMNAHTTNPSR1
	SCHEMBL3576658	0.78	NPSR1 (0.55)	PPARDALDH1A1MAPTLMNAHTT
	SCHEMBL3585588	0.75	NPSR1 (0.54)	ALDH1A1MAPTLMNAHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.