Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 17/20 | 0.52 |
| ▸ | CHUK | O15111 | 15/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591372 | 0.85 | IKBKB (0.52) | IKBKBCHUKEGFR | |
| SCHEMBL3305180 | 0.83 | MEN1 (0.43) | IKBKBCHUKEGFR | |
| SCHEMBL3595943 | 0.82 | IKBKB (0.61) | IKBKBCHUK | |
| SCHEMBL13440368 | 0.78 | IKBKB (0.60) | IKBKBCHUK | |
| SCHEMBL3585027 | 0.76 | IKBKB (0.52) | IKBKBCHUKEGFR | |
| SCHEMBL3586464 | 0.75 | IKBKB (0.51) | IKBKBCHUKEGFR | |
| SCHEMBL3592664 | 0.75 | IKBKB (0.55) | IKBKBCHUKEGFR | |
| SCHEMBL13392085 | 0.75 | RAB9A (0.47) | IKBKBCHUK | |
| SCHEMBL3594326 | 0.75 | IKBKB (0.51) | IKBKBCHUKEGFR | |
| SCHEMBL13392487 | 0.74 | MAPT (0.51) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069417-A1 | NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069417-A1 | NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | IKBKB, NFKBIA, IKBKE | IKBKB 1/4885CHUK 4/4885EGFR 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.