SCHEMBL359179

SCHEMBL359179

Cc1ccc([N+](=O)[O-])c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
CYP3A4 P08684 3/20 0.67
MAPK1 P28482 1/20 0.64
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP13 P45452 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
S1PR4 O95977 1/20 0.49
PDE7A Q13946 1/20 0.49
ALDH1A1 P00352 2/20 0.47
F2 P00734 2/20 0.46
PRSS1 P07477 2/20 0.46
PRSS2 P07478 2/20 0.46
PRSS3 P35030 2/20 0.46
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31281371 1.00 TSHR (0.67) TSHRCYP3A4MAPK1CA1CA2
SCHEMBL30753177 0.83 TSHR (0.67) TSHRCYP3A4TDP1S1PR4ALDH1A1
SCHEMBL84100 0.83 TSHR (0.67) TSHRCYP3A4TDP1S1PR4ALDH1A1
Ammonia Solution, Strong SCHEMBL28193869 0.82 TSHR (0.64) TSHRCYP3A4TDP1S1PR4ALDH1A1
SCHEMBL294724 0.80 TSHR (1.00) TSHRCYP3A4TDP1ALDH1A1MAPT
SCHEMBL9101995 0.80 KMT2A (0.54) CYP3A4MAPK1TDP1ALDH1A1CYP1A2
SCHEMBL2485012 0.79 TSHR (0.64) TSHRCYP3A4MAPK1CA1CA2
SCHEMBL31312499 0.79 TSHR (0.64) TSHRCYP3A4MAPK1CA1CA2
SCHEMBL557939 0.78 TSHR (0.72) TSHRCYP3A4TDP1ALDH1A1MAPT
SCHEMBL29398960 0.78 TSHR (1.00) TSHRMAPK1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118403473-A Gas-water separation membrane framework, normal pressure VOCs self-breathing gas proton separation membrane and application thereof 辽宁东德恩环保科技有限公司 2024-07-30 CN claimed
CN-106633059-B A kind of acetenyl sealing end poly (arylene ether nitrile) imide resin and preparation method thereof 沈阳航空航天大学 2019-02-01 CN claimed
CN-106633059-A Ethynyl terminated polyarylene ether nitrile imide resin and preparation method thereof 沈阳航空航天大学 2017-05-10 CN claimed
CN-106496558-A One kind can response type poly (arylene ether nitrile) imide resin and preparation method thereof 沈阳航空航天大学 2017-03-15 CN claimed
CN-105753713-A Synthetic method for 1,3-bis(5-nitro-2-ethyl formate phenoxy) benzene 常州大学 2016-07-13 CN claimed
CN-104370747-B A kind of method synthesizing the chloro-4-monomethylaniline. of 3- 浙江工业大学 2016-06-08 CN claimed
EP-1493061-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2009-01-07 EP claimed
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US claimed
EP-1493061-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2005-01-05 EP claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
WO-2003087233-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-10-23 WO claimed
EP-0083924-B1 PROCESS FOR THE PREPARATION OF 2-AMINO-5 NITROTOLUENE HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-04 EP claimed
EP-0077537-B1 PROCESS FOR PREPARING 6-CHLORO-3-TOLUIDINO-4-SULPHONIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1985-10-02 EP claimed
US-4124768-A Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids HOECHST AKTIENGESELLSCHAFT 1978-11-07 US claimed
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 EP disclosed
EP-3696167-B1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2024-11-20 EP disclosed
US-4124768-A Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids HOECHST AKTIENGESELLSCHAFT 1978-11-07 US disclosed
US-4045442-A ANTIINFLAMMATORY, ANTIDIARRHEA G. D. SEARLE & CO. (US) 1977-08-30 US disclosed
US-3966830-A SILICA, ALUMINA TEIJIN LIMITED (JA) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 TSHR 363/4885CYP3A4 2054/4885MAPK1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.