Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29486962 | 0.93 | OTC (0.58) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL10005285 | 0.93 | OTC (0.58) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL365299 | 0.93 | OTC (0.58) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL31370284 | 0.85 | ALOX15 (0.62) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL13787905 | 0.84 | ALOX15 (0.56) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL8627837 | 0.83 | OTC (0.51) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL4899060 | 0.83 | OTC (0.51) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL27776403 | 0.83 | GSR (0.58) | OTCNOD1ALOX15BLMPMP22 | |
| SCHEMBL7996973 | 0.83 | OTC (0.55) | OTCNOD1GSRTDP1CYP1A2 | |
| SCHEMBL18924743 | 0.83 | GSR (0.58) | OTCNOD1ALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334498-B1 | METHODS OF TREATING VOLUME DEPLETION AND KIDNEY INJURY | UNIV COLUMBIA (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-11119104-B2 | Methods of treating volume depletion and kidney injury | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-09-14 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-3443001-A2 | REGULATED BIOCIRCUIT SYSTEMS | Obsidian Therapeutics, Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3334498-A1 | METHODS OF TREATING VOLUME DEPLETION AND KIDNEY INJURY | The Trustees of Columbia University in the City of New York (US) | 2018-06-20 | — | — | EP | disclosed |
| EP-2593472-B1 | ANCESTRAL PROTEINS | UNIV COLUMBIA (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9880088-B2 | Force-clamp spectrometer with functionalized cantilever tip | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-01-30 | — | — | US | disclosed |
| US-20180016562-A1 | ANCESTRAL PROTEINS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2018-01-18 | — | — | US | disclosed |
| WO-2017180587-A2 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| WO-2003020897-A2 | COMPOSITIONS AND METHODS RELATING TO OVARY SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020934-A1 | COMPOSITIONS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020900-A2 | COMPOSITIONS AND METHODS RELATING TO BREAST SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020901-A2 | COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020953-A2 | COMPOSITIONS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020899-A2 | COMPOSITIONS AND METHODS RELATING TO LUNG SPECIFIC GENES AND PROTEINS | DIADEXUS, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| US-20020102610-A1 | Automated identification of peptides | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-08-01 | — | — | US | disclosed |
| US-20020055186-A1 | Detection of peptides | OXFORD GLYCOSCIENCES (UK) LTD. | 2002-05-09 | — | — | US | disclosed |
| WO-2002025287-A2 | DETECTION OF PEPTIDES | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002021139-A2 | AUTOMATED IDENTIFICATION OF PEPTIDES | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-03-14 | — | — | WO | disclosed |