SCHEMBL3592775

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3590852	0.78	KCNH3 (0.51)	HDAC3HDAC1HDAC2HDAC6JAK2
	SCHEMBL4422999	0.77	KCNH3 (0.50)	HDAC3HDAC1HDAC2HDAC6PTK2
	SCHEMBL3588812	0.75	HDAC6 (0.39)	HDAC3HDAC1HDAC2HDAC6JAK2
	SCHEMBL3595433	0.73	KDR (0.46)	AURKAALDH1A1CCNT1CCNE1CDK2
	SCHEMBL3592236	0.73	APP (0.55)	AURKACCNT1CCNE1CDK2CDK9
	SCHEMBL14753408	0.71	AURKA (0.54)	AURKAUSP2ALDH1A1CCNT1CCNE1
	SCHEMBL3584904	0.69	SYK (0.58)	AURKAUSP2CYP1A2CYP3A4MAPK1
	SCHEMBL1273068	0.69	NR1I2 (0.41)	HDAC3HDAC1HDAC2HDAC6JAK2
	SCHEMBL1272903	0.69	NR1I2 (0.41)	HDAC3HDAC1HDAC2HDAC6JAK2
	SCHEMBL1272266	0.69	NR1I2 (0.41)	HDAC3HDAC1HDAC2HDAC6JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.