⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38415 | 1.00 | — | — | |
| SCHEMBL1542023 | 0.94 | — | — | |
| SCHEMBL8770024 | 0.84 | — | — | |
| SCHEMBL9011544 | 0.82 | — | — | |
| SCHEMBL8769427 | 0.76 | — | — | |
| SCHEMBL1541129 | 0.76 | — | — | |
| SCHEMBL1541128 | 0.76 | — | — | |
| SCHEMBL1677682 | 0.71 | — | — | |
| SCHEMBL1677681 | 0.71 | — | — | |
| SCHEMBL1542225 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |
| US-7642260-B2 | N-acylsulfonamide derivatives; BCL-X1 protein inhibitors; anticarcinogenic agents; bladder cancer; for example, N-(4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(dimethylamino)-1-((phenylsulfanyl)methyl)-propyl)amino)-3-nitrobenzenesulfonamide | ABBOTT LABORATORIES, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2008-08-14 | — | — | US | disclosed |
| EP-0836635-B1 | Compositions of synthetic polymers and a polysilane derivative | CIBA SC HOLDING AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| US-6005036-A | ADDED TO ORGANIC MATERIAL TO PREVENT OXIDATIVE, THERMAL AND ACTINIC DEGRADATION | CIBA SPECIALTY CHEMICAL CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0836635-A1 | Compositions of synthetic polymers and a polysilane derivative | Ciba SC Holding AG (CH) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002322-A1 | POLYSILANES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-01-23 | — | — | WO | disclosed |
| US-5003074-A | N-fluorinated sulfonamides | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4338316-A | PROSTAGLANDIN F SERIES ANALOGUES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |