⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592948 | 1.00 | — | — | |
| SCHEMBL1542023 | 0.94 | — | — | |
| SCHEMBL8770024 | 0.84 | — | — | |
| SCHEMBL9011544 | 0.82 | — | — | |
| SCHEMBL8769427 | 0.76 | — | — | |
| SCHEMBL1541129 | 0.76 | — | — | |
| SCHEMBL1541128 | 0.76 | — | — | |
| SCHEMBL1677682 | 0.71 | — | — | |
| SCHEMBL1677681 | 0.71 | — | — | |
| SCHEMBL1542225 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509426-B2 | Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability | JAPAN POLYCHEM CORPORATION (JP) | 2003-01-21 | — | — | US | claimed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |
| WO-2024149093-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |
| WO-2024114318-A1 | DRUG LINKER COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024114523-A1 | ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024114531-A1 | HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| CN-118105508-A | Medicinal linker compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2024099911-A1 | IRON CARBONYL COMPLEXES WITH CHIRAL, BIDENTATE BIPHOSPHINE LIGANDS | BASF SE (DE) | 2024-05-16 | — | — | WO | disclosed |
| CN-117651552-A | Therapeutic or prophylactic agent for covd-19 | 国立大学法人广岛大学 | 2024-03-05 | — | — | CN | disclosed |
| US-20240024266-A1 | Therapeutic Agent or Prophylactic Agent for COVID-19 | HIROSHIMA UNIVERSITY (JP) | 2024-01-25 | — | — | US | disclosed |
| US-4861913-A | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| US-4795814-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTTS, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0226346-A1 | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4606933-A | Acrylate-functional organopolysiloxanes | SWS SILICONES CORPORATION (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4338316-A | PROSTAGLANDIN F SERIES ANALOGUES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |