Sugi Predict

Sugi Predict / Compounds / SCHEMBL359362

SCHEMBL359362

SCHEMBL359362

NNc1c(F)c(F)cc(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 5/20 0.41
▸ CA2 P00918 5/20 0.41
▸ CA12 O43570 2/20 0.41
▸ CA7 P43166 2/20 0.41
▸ CA13 Q8N1Q1 2/20 0.41
▸ CA4 P22748 2/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HDAC3 O15379 1/20 0.32
▸ HDAC1 Q13547 1/20 0.32
▸ HDAC2 Q92769 1/20 0.32
▸ HDAC6 Q9UBN7 1/20 0.32
▸ RAPGEF4 Q8WZA2 1/20 0.32
▸ CES2 O00748 1/20 0.31
▸ CES1 P23141 1/20 0.31
▸ CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20984823 0.97 CA1 (0.39) CA1CA2CA12CA7CA13
Bromide SCHEMBL20984704 0.97 CA1 (0.39) CA1CA2CA12CA7CA13
Oxalic Acid SCHEMBL20984624 0.86 CA1 (0.40) CA1CA2CA12CA7CA13
Sulfuric Acid SCHEMBL20984413 0.86 CA1 (0.47) CA1CA2CA12CA7CA13
Phosphoric Acid SCHEMBL20984564 0.86 CA1 (0.38) CA1CA2CA12CA7CA13
SCHEMBL10989839 0.83 CA1 (0.38) CA1CA2CA12CA7CA13
Nitric Acid SCHEMBL20984513 0.82 CA1 (0.38) CA1CA2CA12CA7CA13
Bromide SCHEMBL20985005 0.81 CA1 (0.37) CA1CA2CA12CA7CA13
Hydrochloric Acid SCHEMBL20984615 0.81 CA1 (0.37) CA1CA2CA12CA7CA13
SCHEMBL28856301 0.74 CA12 (0.34) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107915647-A A kind of synthetic method of 2,3,5,6 tetrafluoroaniline 大连奇凯医药科技有限公司 2018-04-17 — — CN claimed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 — — CN claimed
CN-102603687-B Fraxinellone acylhydrazone/hydrazone/ester derivatives and application in preparation of plant source insecticides UNIV NORTHWEST A&F 2013-12-11 — — CN claimed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 — — CN claimed
CN-102603687-A Fraxinellone acylhydrazone/hydrazone/ester derivatives and application in preparation of plant source insecticides UNIV NORTHWEST A&F 2012-07-25 — — CN claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 — — US claimed
CN-106946737-B Pyrene-fluorobenzene hydrazone and its preparation method and application 郑州大学 2019-03-22 — — CN disclosed
EP-2166412-B1 Method of producing a polymerized carbon nanotube composite using a composition comprising carboxylated carbon nanotubes surface-modified with polymerizable moieties SAMSUNG ELECTRONICS CO LTD (KR) 2019-01-16 — — EP disclosed
CN-103936538-B Method for preparing phenol by performing catalytic oxidation on aryl boron compound 南京师范大学 2017-02-15 — — CN disclosed
US-9493436-B2 Tyrosine phosphatase inhibitors and uses thereof to modulate the activity of enzymes involved in the pathology of Mycobacterium tuberculosis INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-11-15 — — US disclosed
US-9493436-B2 Tyrosine phosphatase inhibitors and uses thereof to modulate the activity of enzymes involved in the pathology of Mycobacterium tuberculosis INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-11-15 — — US disclosed
EP-2593453-B1 AZAINDAZOLE COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2014-09-17 — — EP disclosed
CN-103936538-A Method for preparing phenol by performing catalytic oxidation on aryl boron compound UNIV NANJING NORMAL 2014-07-23 — — CN disclosed
US-20050096471-A1 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 — — US disclosed
US-20040265755-A1 Surface treatment of interpenetrating polymer networkcarbon tubes; photolithography; heat curing; negative patterns SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-12-30 — — US disclosed
EP-1473286-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-03 — — EP disclosed
CN-1530404-A Preparations of carbon nano tube layout film or composite material from polymerisable semgental surface modified carbon nano tubes ���ǵ�����ʽ���� 2004-09-22 — — CN disclosed
WO-2004078732-A1 N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF AVENTIS PHARMA S.A. (FR) 2004-09-16 — — WO disclosed
EP-1457821-A1 Method of making carbon nanotube patterned film or carbon nanotube composite material using a composition comprising carbon nanotubes surface-modified with polymerizable moieties Samsung Electronics Co., Ltd. (KR) 2004-09-15 — — EP disclosed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096471-A1 Process for producing biaryl compound PPOX, CAT, TYR CA1 3383/4885CA2 2297/4885CA12 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.