Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.51 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593639 | 1.00 | NR3C1 (0.51) | NR3C1SMOPGR | |
| SCHEMBL3597037 | 0.89 | NR3C1 (0.51) | NR3C1SMOPGR | |
| SCHEMBL3597041 | 0.89 | NR3C1 (0.51) | NR3C1SMOPGR | |
| SCHEMBL3587123 | 0.88 | NR3C1 (0.47) | NR3C1SMOPGR | |
| SCHEMBL3587124 | 0.88 | NR3C1 (0.47) | NR3C1SMOPGR | |
| SCHEMBL3599365 | 0.84 | NR3C1 (0.51) | NR3C1SMOPGR | |
| SCHEMBL3599363 | 0.84 | NR3C1 (0.51) | NR3C1SMOPGR | |
| SCHEMBL29205228 | 0.76 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL834718 | 0.75 | NR3C1 (0.72) | NR3C1PGR | |
| SCHEMBL834719 | 0.75 | NR3C1 (0.72) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728030-B2 | Chemical compounds 572 | ASTRAZENECA AB (SE) | 2010-06-01 | — | — | US | disclosed |