Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.73 |
| ▸ | CA2 | P00918 | 16/20 | 0.73 |
| ▸ | CA9 | Q16790 | 11/20 | 0.71 |
| ▸ | CA12 | O43570 | 10/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19814892 | 0.86 | NT5E (0.57) | CA1CA2CA9CA12MAPT | |
| SCHEMBL27747721 | 0.86 | CA1 (0.76) | CA1CA2CA9CA12MAPT | |
| SCHEMBL3494987 | 0.84 | LMNA (0.58) | CA1CA2CA9CA12MAPT | |
| SCHEMBL4522845 | 0.84 | CA1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL361047 | 0.84 | CA1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL7495027 | 0.84 | CA1 (0.69) | CA1CA2CA9CA12MAPT | |
| SCHEMBL1593097 | 0.84 | CA1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL1395590 | 0.83 | CA1 (1.00) | CA1CA2CA9CA12MAPT | |
| Hydrochloric Acid SCHEMBL2433442 | 0.83 | CA1 (0.62) | CA1CA2CA9CA12MAPT | |
| SCHEMBL14289838 | 0.81 | CA1 (0.74) | CA1CA2CA9CA12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243063-A | Sulfonamide derivatives having carbonic anhydrase inhibiting activity and their use as therapeutic and diagnostic agents | UNION LIFE SCIENCE LTD (GB) | 2008-08-13 | — | — | CN | claimed |
| CN-102099337-B | Piperazine derivatives useful as CAV2.2 calcium channel modulators | CONVERGENCE PHARMACEUTICALS | 2013-08-21 | — | — | CN | disclosed |
| CN-102066123-B | Color-developing composition and recording material containing same | NIPPON SODA CO | 2013-07-03 | — | — | CN | disclosed |
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| CN-102099337-A | Piperazine derivatives useful as CAV2.2 calcium channel modulators | CONVERGENCE PHARMACEUTICALS | 2011-06-15 | — | — | CN | disclosed |
| CN-102066123-A | Color-developing composition and recording material containing same | NIPPON SODA CO | 2011-05-18 | — | — | CN | disclosed |
| CN-101243063-A | Sulfonamide derivatives having carbonic anhydrase inhibiting activity and their use as therapeutic and diagnostic agents | UNION LIFE SCIENCE LTD (GB) | 2008-08-13 | — | — | CN | disclosed |
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |