Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29774590 | 1.00 | PLD1 (0.58) | PLD1GPR119TSHRMEN1PKM | |
| Ammonia Solution, Strong SCHEMBL8126869 | 0.98 | PLD1 (0.56) | PLD1GPR119TSHRMEN1PKM | |
| SCHEMBL8091809 | 0.89 | GRM1 (0.51) | PLD1GPR119TSHRMEN1PKM | |
| SCHEMBL23875675 | 0.89 | GRM1 (0.51) | PLD1GPR119TSHRMEN1PKM | |
| SCHEMBL21353591 | 0.82 | — | — | |
| SCHEMBL15800694 | 0.82 | PLD1 (0.73) | PLD1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL29857922 | 0.82 | PLD1 (0.73) | PLD1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL17619606 | 0.82 | GPR119 (0.52) | PLD1GPR119KDM4EALDH1A1MAPT | |
| SCHEMBL1245662 | 0.81 | PLD1 (0.58) | PLD1GPR119KDM4EALDH1A1POLB | |
| SCHEMBL243658 | 0.81 | PLD1 (0.58) | PLD1GPR119TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |
| EP-3535269-B1 | [1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS PDE2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-09 | — | — | EP | disclosed |
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2020-12-03 | — | — | US | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-5939233-A | PHOTOGRAPHIC FILMS WITH SULFONAMIDO HYDRAZIDES HAVING PYRIDINIUM GROUPS | KODAK POLYCHROME GRAPHICS LLC (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0126951-B1 | Phase transfer catalysts | GEN ELECTRIC (US) | 1994-07-20 | — | — | EP | disclosed |
| US-H1313-H | From polyepichlorohydrin and alkali azides, quaternary ammonium catalysts | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| EP-0252964-B1 | CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING SUBSTITUTED PYRIDINIUM SALTS | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4973772-A | Catalytic method for producing fluoroarmatic compounds using substituted pyridinium salts | MALLINCKRODT, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0252964-A4 | CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING SUBSTITUTED PYRIDINIUM SALTS. | MALLINCKRODT INC (US) | 1988-07-14 | — | — | EP | disclosed |
| EP-0252964-A1 | CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING SUBSTITUTED PYRIDINIUM SALTS. | MALLINCKRODT INC (US) | 1988-01-20 | — | — | EP | disclosed |
| WO-1987004150-A1 | CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING SUBSTITUTED PYRIDINIUM SALTS | MALLINCKRODT, INC. (US) | 1987-07-16 | — | — | WO | disclosed |
| EP-0126951-A2 | Phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4460778-A | ALKYLDIORGANOAMINOPYRIDINIUM SALTS FOR MAKING AROMATIC ETHER IMIDES | GENERAL ELECTRIC COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377510-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | SHARPIN, PIR, THPO | PLD1 441/4885GPR119 2054/4885TSHR 3596/4885 |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | PLD1 1370/4885GPR119 2282/4885TSHR 4664/4885 |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | PLD1 2164/4885GPR119 190/4885TSHR 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.