Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.76 |
| ▸ | CDC25B | P30305 | 3/20 | 0.49 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158309 | 0.86 | IDO1 (1.00) | IDO1EP300KAT2BKAT8GAA | |
| SCHEMBL8147899 | 0.85 | IDO1 (0.58) | IDO1CDC25BEP300KAT2BKAT8 | |
| SCHEMBL2770442 | 0.79 | CDC25B (0.50) | IDO1CDC25BEP300KAT2BKAT8 | |
| SCHEMBL4583715 | 0.78 | EP300 (0.80) | IDO1CDC25BEP300KAT2BKAT8 | |
| SCHEMBL28327 | 0.77 | IDO1 (0.73) | IDO1EP300KAT2BKAT8CDK2 | |
| SCHEMBL29351230 | 0.77 | IDO1 (0.73) | IDO1EP300KAT2BKAT8CDK2 | |
| SCHEMBL4869305 | 0.77 | IDO1 (0.73) | IDO1EP300KAT2BKAT8CDK2 | |
| SCHEMBL11411652 | 0.77 | IDO1 (0.79) | IDO1CDC25BEP300KAT2BKAT8 | |
| SCHEMBL5510298 | 0.77 | IDO1 (0.52) | IDO1CDC25BEP300KAT2BKAT8 | |
| SCHEMBL17715571 | 0.76 | HPGD (0.52) | IDO1TRPV1CDK2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072584-B | Near-infrared fluorescent small molecule probe and preparation and application thereof | 南京科技职业学院 | 2022-06-24 | — | — | CN | claimed |
| CN-111072584-A | Near-infrared fluorescent small molecule probe and preparation and application thereof | 南京科技职业学院 | 2020-04-28 | — | — | CN | claimed |
| CN-111072584-B | Near-infrared fluorescent small molecule probe and preparation and application thereof | 南京科技职业学院 | 2022-06-24 | — | — | CN | disclosed |
| US-11078214-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2021-08-03 | — | — | US | disclosed |
| CN-111072584-A | Near-infrared fluorescent small molecule probe and preparation and application thereof | 南京科技职业学院 | 2020-04-28 | — | — | CN | disclosed |
| US-10457688-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2019-10-29 | — | — | US | disclosed |
| US-9994586-B2 | Monocyclic, thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of the same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-06-12 | — | — | US | disclosed |
| WO-2017031176-A1 | MONOCYCLIC, THIENO, PYRIDO, AND PYRROLO PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE OF THE SAME | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20170050978-A1 | Monocyclic, Thieno, Pyrido, and Pyrrolo Pyrimidine Compounds and Methods of Use and Manufacture of the Same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2017-02-23 | — | — | US | disclosed |
| CN-103298772-B | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2015-06-24 | — | — | CN | disclosed |
| CN-103298772-A | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2013-09-11 | — | — | CN | disclosed |
| EP-1765821-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. | 2006-04-06 | — | — | US | disclosed |
| WO-2005123069-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-0326223-B1 | Copolymer composition | SHELL INT RESEARCH (NL) | 1996-05-08 | — | — | EP | disclosed |
| CN-1034740-A | Copolymer compositions | SHELL INT RESEARCH (NL) | 1989-08-16 | — | — | CN | disclosed |
| US-4855427-A | Epoxy resins obtained from reaction of epoxyalkyl halides and aromatic hydroxyl-containing melamines | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0326223-A2 | Copolymer composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-08-02 | — | — | EP | disclosed |
| US-4795774-A | OXIDATION RESISTANCE BY INCORPORATING AN AROMATIC AMINE STABILIZER | SHELL OIL COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0296493-A2 | Epoxy resins | BASF Aktiengesellschaft (DE) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | MGAM, GSK3B, GSK3A | IDO1 1133/4885CDC25B 3073/4885EP300 1791/4885 |
| US-11078214-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DPYD, TYMS, THPO | IDO1 1580/4885CDC25B 341/4885EP300 3562/4885 |
| US-10457688-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DPYD, TPX2, TYMS | IDO1 1194/4885CDC25B 430/4885EP300 2544/4885 |
| US-20170050978-A1 | Monocyclic, Thieno, Pyrido, and Pyrrolo Pyrimidine Compounds and Methods of Use and Manufacture of the Same | CYP4F3, TYMS, DPYD | IDO1 765/4885CDC25B 2063/4885EP300 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.