SCHEMBL4583715

SCHEMBL4583715

CS(=O)(=O)Nc1cccc2c(O)cccc12

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.80
KAT2B Q92831 2/20 0.80
KAT8 Q9H7Z6 2/20 0.80
KEAP1 Q14145 2/20 0.62
HSD17B1 P14061 1/20 0.51
HSD17B2 P37059 1/20 0.51
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
NFE2L2 Q16236 1/20 0.50
KDM4E B2RXH2 1/20 0.50
JAK2 O60674 1/20 0.49
JAK1 P23458 1/20 0.49
IDO1 P14902 1/20 0.48
PARP14 Q460N5 1/20 0.48
CDK2 P24941 1/20 0.47
PLA2G7 Q13093 1/20 0.47
GAA P10253 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HKDC1 Q2TB90 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15894583 0.89 EP300 (1.00) EP300KAT2BKAT8KEAP1HPGD
SCHEMBL30669737 0.89 EP300 (1.00) EP300KAT2BKAT8KEAP1HPGD
SCHEMBL11509065 0.88 KEAP1 (0.77) EP300KAT2BKAT8KEAP1HPGD
SCHEMBL17774591 0.81 EP300 (0.58) EP300KAT2BKAT8KEAP1HSD17B1
SCHEMBL6111717 0.80 EP300 (0.61) EP300KAT2BKAT8KEAP1HSD17B2
SCHEMBL5965425 0.79 KEAP1 (0.67) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL28750618 0.79 KMT2A (0.60) EP300KAT2BKAT8KEAP1HPGD
SCHEMBL7028887 0.78 EP300 (0.55) EP300KAT2BKAT8KEAP1HPGD
SCHEMBL3594546 0.78 IDO1 (0.76) EP300KAT2BKAT8HPGDHSD17B10
SCHEMBL6806702 0.78 KEAP1 (0.59) EP300KAT2BKAT8KEAP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975202-A2 Novel azo compound and azo dye FUJIFILM Corporation (JP) 2008-10-01 EP disclosed
EP-1398022-B1 Method of dyeing hair characterised by use of an azo dye containing a dissociative proton KAO CORP (JP) 2008-03-19 EP disclosed
US-7056355-B2 Hair dye composition and dyeing method KAO CORPORATION (JP) 2006-06-06 US disclosed
US-20050015896-A1 Hair dye composition and dyeing method KAO CORPORATION (JP) 2005-01-27 US disclosed
EP-1398022-A1 Hair dye composition comprising an azo dye containing a dissociative proton, method and use Kao Corporation (JP) 2004-03-17 EP disclosed
EP-1398020-A1 Hair dye composition comprising an azo dye containing a dissociative proton, method and use Kao Corporation (JP) 2004-03-17 EP disclosed
US-5342730-A With mordant and stripping layers EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
EP-0394563-B1 Cyan dyes in dye-donor elements for thermal dye transfer AGFA GEVAERT NV (BE) 1994-03-09 EP disclosed
US-5021393-A Stable quinonediimine dyes AGFA-GEVAERT, N.V. (BE) 1991-06-04 US disclosed
EP-0394563-A1 Cyan dyes in dye-donor elements for thermal dye transfer AGFA-GEVAERT N.V. (BE) 1990-10-31 EP disclosed
US-4956456-A POLYACRYLONITRILE FIBERS, DACRON\" FIBERS FUJI PHOTO FILM CO., LTD. (JP) 1990-09-11 US disclosed
EP-0143310-B1 COLOR LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-08-24 EP disclosed
US-4556632-A CONTAINING CYAN AZO DYE RELEASING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1985-12-03 US disclosed
US-4529692-A Containing a naphthalene ring with a sulfonamide group FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
EP-0143310-A2 Color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-06-05 EP disclosed
US-4278598-A AZO DYES EASTMAN KODAK COMPANY (US) 1981-07-14 US disclosed
US-4268606-A Azo dye compounds and photographic materials EASTMAN KODAK COMPANY (US) 1981-05-19 US disclosed
US-4199354-A BALLASTED IMAGE-DYE PROVIDING MATERIALS EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-3932381-A DIFFUSION TRANSFER COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050015896-A1 Hair dye composition and dyeing method SULT1A1, CYP21A2, SULT2A1 EP300 3213/4885KAT2B 512/4885KAT8 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.