Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172360 | 1.00 | GCK (0.37) | GCKPLA2G2AGRNSORT1RARA | |
| SCHEMBL3603264 | 0.85 | PLA2G2A (0.35) | PLA2G2AGRNSORT1THRATHRB | |
| SCHEMBL3605375 | 0.85 | GCK (0.49) | GCKPLA2G2ARARARARBRARG | |
| SCHEMBL14538226 | 0.84 | GCK (0.37) | GCKGRNSORT1RARARARB | |
| SCHEMBL3594161 | 0.84 | GCK (0.40) | GCKRARARARBKMT2A | |
| SCHEMBL12408469 | 0.81 | GCK (0.50) | GCKRARGKMT2A | |
| SCHEMBL3595682 | 0.78 | GCK (0.35) | GCKPLA2G2ARARARARBTHRA | |
| SCHEMBL29784105 | 0.78 | KMT2A (0.55) | GCKPLA2G2ARARARARBTHRA | |
| SCHEMBL2657385 | 0.78 | KMT2A (0.55) | GCKPLA2G2ARARARARBTHRA | |
| SCHEMBL3588948 | 0.77 | MEN1 (0.48) | GCKRARARARBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039901-B | Process for making phenoxy benzamide compounds | ASTRAZENECA AB | 2011-03-09 | — | — | CN | disclosed |
| US-7700640-B2 | Process for making phenoxy benzamide compounds | ASTRAZENECA AB (SE) | 2010-04-20 | — | — | US | disclosed |
| CN-101316815-A | Chemical process for the preparation of an amido-phenoxybenzoic acid compound | ASTRAZENECA AB (SE) | 2008-12-03 | — | — | CN | disclosed |
| US-20080200694-A1 | Process for Making Phenoxy Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | US | disclosed |
| CN-101039901-A | Process for making phenoxy benzamide compounds | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | CN | disclosed |
| EP-1802570-A1 | PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS | AstraZeneca AB (SE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040527-A1 | PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200694-A1 | Process for Making Phenoxy Benzamide Compounds | PAH, MAOB, TYR | GCK 1415/4885PLA2G2A 3616/4885GRN 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.