Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103788 | 0.87 | NR1H2 (0.68) | NR1H3NR1H2 | |
| SCHEMBL102900 | 0.79 | NR1H2 (0.69) | NR1H3NR1H2 | |
| SCHEMBL105121 | 0.76 | NR1H2 (0.68) | NR1H3NR1H2 | |
| SCHEMBL103650 | 0.76 | NR1H2 (0.54) | NR1H3NR1H2 | |
| SCHEMBL15369643 | 0.76 | NR1H2 (0.50) | NR1H3NR1H2 | |
| SCHEMBL105506 | 0.74 | NR1H2 (0.65) | NR1H3NR1H2 | |
| SCHEMBL171577 | 0.74 | NR1H2 (0.66) | NR1H3NR1H2 | |
| SCHEMBL542381 | 0.74 | NR1H3 (1.00) | NR1H3NR1H2 | |
| SCHEMBL543170 | 0.73 | NR1H3 (0.59) | NR1H3NR1H2 | |
| SCHEMBL105129 | 0.72 | NR1H2 (0.63) | NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-B1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | KOWA CO (JP) | 2013-11-06 | — | — | EP | disclosed |
| US-8551985-B2 | Carbinol derivatives having heterocyclic linker | KOWA COMPANY, LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20100280013-A1 | CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER | KOWA COMPANY, LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280013-A1 | CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER | NR1H2, NR1H3, CCR2 | NR1H3 2/4885NR1H2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.