⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913699 | 0.89 | — | — | |
| SCHEMBL2049187 | 0.81 | — | — | |
| SCHEMBL7737963 | 0.73 | — | — | |
| SCHEMBL3800070 | 0.73 | — | — | |
| SCHEMBL6605645 | 0.73 | — | — | |
| SCHEMBL7733149 | 0.73 | — | — | |
| SCHEMBL7741569 | 0.73 | — | — | |
| SCHEMBL247765 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL7658464 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL18549756 | 0.69 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780935-B2 | Mutant antibodies and conjugation thereof | PFIZER HEALTHCARE IRELAND (IE) | 2023-10-10 | — | — | US | disclosed |
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | PFIZER HEALTHCARE IRELAND (IE) | 2021-05-20 | — | — | US | disclosed |
| EP-2593142-B1 | MULTIFUNCTIONAL ANTIBODY CONJUGATES | COVX TECH IRELAND LIMITED (IE) | 2018-10-10 | — | — | EP | disclosed |
| EP-2802355-B1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | COVX TECH IRELAND LIMITED (IE) | 2018-09-05 | — | — | EP | disclosed |
| EP-3049391-A1 | INDOL AND INDAZOL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-08-03 | — | — | EP | disclosed |
| CN-101611053-B | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND LTD | 2015-06-03 | — | — | CN | disclosed |
| WO-2015044072-A1 | INDOL AND INDAZOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-02 | — | — | WO | disclosed |
| US-20150057431-A1 | COMPOSITIONS FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH ABNORMAL ANGIOGENESIS | COVX TECHNOLOGIES IRELAND LTD (IE) | 2015-02-26 | — | — | US | disclosed |
| US-8937048-B2 | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2015-01-20 | — | — | US | disclosed |
| US-8912148-B2 | Methods of treating a disease or condition associated with abnormal angiogenesis | COVX TECHNOLOGY IRELAND, LTD. (IE) | 2014-12-16 | — | — | US | disclosed |
| US-20060074202-A1 | Stabilized polycarbonate polyester composition | GENERAL ELECTRIC COMPANY | 2006-04-06 | — | — | US | disclosed |
| US-20060074155-A1 | Halogen-free flame retardant polyester | GENERAL ELECTRIC COMPANY | 2006-04-06 | — | — | US | disclosed |
| US-20060069236-A1 | Polyethersulfone compositions with high heat and good impact resistance | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| US-20060069222-A1 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| US-20060066004-A1 | Method for controlling haze in an article comprising a polymer composition | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| US-20060069291-A1 | Phosphazenium salt phase transfer catalysts | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| EP-1640403-A2 | Polyethersulfone compositions with high heat and good impact resistance | GENERAL ELECTRIC COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1640067-A2 | Phosphazenium salt phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004091542-A2 | NITROGEN CONTAINING INTEGRIN TARGETING COMPOUNDS | COVX PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| US-6388044-B1 | THERMOSETTING POLYETHER; CROSSLINKING BY HEATING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |