SCHEMBL359841

SCHEMBL359841

Clc1ccc2ncccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.70
NPC1 O15118 4/20 0.63
RAB9A P51151 3/20 0.63
POLB P06746 2/20 0.63
ALDH1A1 P00352 3/20 0.59
HTT P42858 3/20 0.59
MAPT P10636 3/20 0.59
ATM Q13315 2/20 0.59
KDM4E B2RXH2 1/20 0.59
TP53 P04637 1/20 0.59
HSP90AA1 P07900 1/20 0.59
HSP90AB1 P08238 1/20 0.59
TSHR P16473 1/20 0.59
CASP1 P29466 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CASP6 P55212 1/20 0.53
DOT1L Q8TEK3 2/20 0.51
DYRK1A Q13627 1/20 0.50
MEN1 O00255 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28220148 0.98 NR4A2 (0.68) NR4A2NPC1RAB9APOLBALDH1A1
Pyridine SCHEMBL10954884 0.91 NR4A2 (0.59) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL10784946 0.84 NPC1 (0.78) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL29393522 0.83 NR4A2 (1.00) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL317870 0.83 NR4A2 (1.00) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL31061987 0.82 NR4A2 (0.53) NR4A2NPC1RAB9APOLBALDH1A1
Hydrochloric Acid SCHEMBL30899592 0.81 NR4A2 (0.96) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL29096114 0.81 NR4A2 (0.96) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL29962410 0.81 NR4A2 (0.96) NR4A2NPC1RAB9APOLBALDH1A1
SCHEMBL27988345 0.80 MET (0.55) NR4A2NPC1RAB9APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801596-B Photosensitive polyimide resin composition and preparation method and application thereof 深圳先进电子材料国际创新研究院 2025-04-25 CN claimed
CN-118204084-A Preparation method of silicon oxide modified metal-based catalyst and application of silicon oxide modified metal-based catalyst in preparation of cyclic amine compounds 浙江恒逸石化研究院有限公司 2024-06-18 CN claimed
CN-118126272-A Preparation and application of novel transfer hydrogenation catalyst 中国人民武装警察部队后勤学院 2024-06-04 CN claimed
CN-117924168-A Synthesis method of carbamazepine intermediate 6-quinoline propanal 上海睿腾医药科技有限公司 2024-04-26 CN claimed
CN-115138355-B Hydroxyl modified carbon catalytic hydrogenation material based on hydrogen overflow and preparation method and application thereof 西北工业大学 2024-01-16 CN claimed
CN-115350189-B Application of sinomenine derivative in preparation of medicines for treating colorectal cancer 兰州大学 2023-05-30 CN claimed
CN-115350189-A Application of neocelandine derivative in preparation of medicine for treating colorectal cancer 兰州大学 2022-11-18 CN claimed
CN-115138355-A Hydroxyl modified carbon catalytic hydrogenation material based on hydrogen overflow and preparation method and application thereof 西北工业大学 2022-10-04 CN claimed
CN-112250628-B Method for preparing tetrahydroquinoline compound by catalytic hydrogenation of ruthenium catalyst 上海应用技术大学 2022-07-08 CN claimed
CN-114014858-A Process for preparing polysubstituted indolizine derivatives 淮阴师范学院 2022-02-08 CN claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
EP-0744399-B1 Conversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines AMERICAN CYANAMID CO (US) 2000-10-25 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
CN-1043717-A Cephalosporin compound TANABE SEIYAKU CO (JP) 1990-07-11 CN claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4795621-A CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND SHIN NISSO KAKO CO., LTD. (JP) 1989-01-03 US claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed