Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679546 | 0.93 | SCN4A (0.54) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL21091220 | 0.81 | SCN4A (0.53) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL210148 | 0.81 | AXL (0.60) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL29801372 | 0.81 | AXL (0.60) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL359912 | 0.79 | KMT2A (0.36) | SCN4AEPHX2MPLHSD17B10HPGD | |
| SCHEMBL360218 | 0.75 | AXL (0.53) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL19709634 | 0.75 | AXL (0.53) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL1829710 | 0.75 | AXL (0.53) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL1638626 | 0.75 | AXL (0.53) | SCN4AEPHX2AXLGFERSMN1; SMN2 | |
| SCHEMBL30002611 | 0.75 | SMN1; SMN2 (0.72) | SCN4AEPHX2AXLGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |