Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600930 | 0.88 | DPP4 (0.46) | DPP4DPP8CYP3A4 | |
| SCHEMBL3596892 | 0.86 | DPP4 (0.44) | DPP4DPP8CYP3A4 | |
| SCHEMBL3601749 | 0.85 | DPP4 (0.47) | DPP4DPP8NPC1LMNAPKM | |
| SCHEMBL3088284 | 0.84 | DPP4 (0.43) | DPP4DPP8CNR1CYP3A4 | |
| SCHEMBL3601327 | 0.84 | DPP4 (0.43) | DPP4DPP8CNR1CYP3A4 | |
| SCHEMBL3601689 | 0.82 | DPP4 (0.46) | DPP4DPP8NPC1LMNAPKM | |
| SCHEMBL3091767 | 0.81 | DPP4 (0.50) | DPP4DPP8CNR1 | |
| SCHEMBL3600855 | 0.80 | DPP4 (0.45) | DPP4DPP8CYP3A4 | |
| SCHEMBL3600802 | 0.79 | DPP4 (0.44) | DPP4DPP8CNR1 | |
| SCHEMBL3096850 | 0.79 | DPP4 (0.44) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |