Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.44 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596892 | 0.92 | DPP4 (0.44) | DPP4DPP8CYP3A4HSD11B1KDM4C | |
| SCHEMBL3088284 | 0.90 | DPP4 (0.43) | DPP4DPP8CYP3A4HSD11B1KDM4C | |
| SCHEMBL3601327 | 0.90 | DPP4 (0.43) | DPP4DPP8CYP3A4HSD11B1KDM4C | |
| SCHEMBL3600280 | 0.88 | DPP4 (0.41) | DPP4DPP8CYP3A4 | |
| SCHEMBL3091767 | 0.87 | DPP4 (0.50) | DPP4DPP8CRHR1HSD11B1 | |
| SCHEMBL3600855 | 0.86 | DPP4 (0.45) | DPP4DPP8CYP3A4HSD11B1KDM4C | |
| SCHEMBL3096850 | 0.85 | DPP4 (0.44) | DPP4DPP8CYP3A4 | |
| SCHEMBL3600802 | 0.85 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3596963 | 0.84 | DPP4 (0.58) | DPP4DPP8CYP3A4 | |
| SCHEMBL4660649 | 0.84 | DPP4 (0.48) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |