Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RGS12 | O14924 | 3/20 | 0.46 |
| ▸ | GMNN | O75496 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600538 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3606074 | 0.89 | ALDH1A1 (0.68) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3606077 | 0.89 | ALDH1A1 (0.68) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3596498 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3596496 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3610757 | 0.79 | TP53 (0.47) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3610764 | 0.79 | TP53 (0.47) | ALDH1A1POLBATMKDM4EKMT2A | |
| SCHEMBL3614719 | 0.76 | ALDH1A1 (0.75) | ALDH1A1POLBATMKMT2AMAPK1 | |
| SCHEMBL3614715 | 0.76 | ALDH1A1 (0.75) | ALDH1A1POLBATMKMT2AMAPK1 | |
| SCHEMBL3604145 | 0.73 | ALDH1A1 (0.86) | ALDH1A1POLBKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | claimed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | claimed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | claimed |
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | disclosed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | PDLIM5, PSD, PDCD6IP | ALDH1A1 3764/4885POLB 4582/4885ATM 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.