Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599029 | 0.92 | DRD4 (0.52) | DRD4MLLT1SMYD3KDRHRH4 | |
| SCHEMBL3599033 | 0.92 | DRD4 (0.52) | DRD4MLLT1SMYD3KDRHRH4 | |
| SCHEMBL3599027 | 0.92 | DRD4 (0.52) | DRD4MLLT1SMYD3KDRHRH4 | |
| Trifluoroacetic Acid SCHEMBL3615735 | 0.92 | MLLT1 (0.49) | MLLT1HDAC4SMYD3KDRHDAC6 | |
| Trifluoroacetic Acid SCHEMBL3610931 | 0.88 | SMYD3 (0.49) | MLLT1HDAC4SMYD3HDAC6 | |
| Trifluoroacetic Acid SCHEMBL3610457 | 0.88 | SMYD3 (0.49) | MLLT1HDAC4SMYD3HDAC6 | |
| Trifluoroacetic Acid SCHEMBL3606654 | 0.86 | KDR (0.52) | MLLT1KDRPARP1 | |
| SCHEMBL3612490 | 0.86 | DRD4 (0.50) | DRD4MLLT1HRH4PARP1 | |
| SCHEMBL3612493 | 0.86 | DRD4 (0.50) | DRD4MLLT1HRH4PARP1 | |
| Trifluoroacetic Acid SCHEMBL3612516 | 0.86 | SMYD3 (0.41) | MLLT1HDAC4SMYD3KDRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | IDO2, IDO1, INMT | DRD4 2343/4885MLLT1 2603/4885HDAC4 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.