Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600310 | 0.91 | ABCG2 (0.52) | ABCG2MEN1KMT2APDE5ALMNA | |
| SCHEMBL3409105 | 0.91 | ABCG2 (0.52) | ABCG2MEN1KMT2APDE5AGAA | |
| SCHEMBL3413002 | 0.91 | ABCG2 (0.54) | ABCG2MEN1KMT2APDE5ALMNA | |
| SCHEMBL3415833 | 0.91 | MAPT (0.52) | ABCG2MEN1KMT2ALMNAMAPT | |
| SCHEMBL16139155 | 0.91 | MAPT (0.47) | ABCG2MEN1KMT2ALMNAMAPT | |
| SCHEMBL19453194 | 0.89 | ABL1 (0.46) | ABCG2MEN1KMT2APDE5ALMNA | |
| SCHEMBL14861915 | 0.89 | ABCG2 (0.56) | ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL16492396 | 0.88 | ABCG2 (0.55) | ABCG2PDE5AGAAMAPTKDM4E | |
| SCHEMBL3408510 | 0.88 | ABCG2 (0.56) | ABCG2MEN1KMT2APDE5ALMNA | |
| SCHEMBL3592180 | 0.88 | MAPT (0.55) | ABCG2MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | claimed |
| US-20180044341-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES FOR USE AS BCRP INHIBITORS IN THERAPEUTIC TREATMENTS | DRITTE PATENTPORTFOLIO BETEILIGUNGS-GESELLSCHAFT MBH & CO. KG (DE) | 2018-02-15 | — | — | US | claimed |
| EP-3064207-B1 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | SCANDION ONCOLOGY AS (DK) | 2017-12-20 | — | — | EP | claimed |
| US-9790225-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2017-10-17 | — | — | US | claimed |
| EP-3064207-A1 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2016-09-07 | — | — | EP | claimed |
| US-8962634-B2 | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2015-02-24 | — | — | US | claimed |
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2014-10-02 | — | — | US | claimed |
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | disclosed |
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | disclosed |
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | disclosed |
| US-10975079-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | SCANDION ONCOLOGY A/S (DK) | 2021-04-13 | — | — | US | disclosed |
| US-10975079-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | SCANDION ONCOLOGY A/S (DK) | 2021-04-13 | — | — | US | disclosed |
| US-10975079-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | SCANDION ONCOLOGY A/S (DK) | 2021-04-13 | — | — | US | disclosed |
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2014-10-02 | — | — | US | disclosed |
| EP-2766367-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS ANTIVIRAL ACTIVE SUBSTANCES | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2014-08-20 | — | — | EP | disclosed |
| CN-103946224-A | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d] pyrimidine derivatives, their manufacture and their use as antiviral active substances | DRITTE PATENTPORTFOLIO BETEILI | 2014-07-23 | — | — | CN | disclosed |
| WO-2013053942-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D] PYRIMIDINE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS ANTIVIRAL ACTIVE SUBSTANCES | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2013-04-18 | — | — | WO | disclosed |
| WO-2013053942-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D] PYRIMIDINE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS ANTIVIRAL ACTIVE SUBSTANCES | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2013-04-18 | — | — | WO | disclosed |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | POLL, RPP30, EIF2AK2 | ABCG2 1780/4885MEN1 4757/4885KMT2A 3508/4885 |
| US-20180044341-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES FOR USE AS BCRP INHIBITORS IN THERAPEUTIC TREATMENTS | ABCB1, ABCC1, MPHOSPH6 | ABCG2 5/4885MEN1 4872/4885KMT2A 2807/4885 |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | PNP, TYMP, EIF2AK2 | ABCG2 136/4885MEN1 4838/4885KMT2A 3580/4885 |
| US-10975079-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments | ABCB1, ABCC1, MPHOSPH6 | ABCG2 5/4885MEN1 4872/4885KMT2A 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.