Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409100 | 0.90 | ABCG2 (0.45) | ABCG2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL3602136 | 0.88 | ABCG2 (0.47) | ABCG2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL3413002 | 0.87 | ABCG2 (0.54) | ABCG2ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL29648256 | 0.86 | LMNA (0.48) | ABCG2LMNAHPGDGRM4 | |
| SCHEMBL16492396 | 0.86 | ABCG2 (0.55) | ABCG2ABCC1FADS1DPP4KDM4E | |
| SCHEMBL3592180 | 0.86 | MAPT (0.55) | ABCG2LMNAHPGDKMT2AL3MBTL1 | |
| SCHEMBL14861582 | 0.86 | LMNA (0.48) | ABCG2LMNAHPGDGRM4 | |
| SCHEMBL16492388 | 0.83 | ABCG2 (0.57) | ABCG2ABCC1KMT2ADPP4MEN1 | |
| SCHEMBL16140867 | 0.82 | ABCG2 (0.60) | ABCG2GRM4 | |
| SCHEMBL3408507 | 0.81 | ABL1 (0.54) | ABCG2ALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962634-B2 | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2015-02-24 | — | — | US | claimed |
| EP-2049540-B1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-12-22 | — | — | EP | claimed |
| EP-2049540-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co.KG (DE) | 2009-04-22 | — | — | EP | claimed |
| WO-2007147401-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO.KG (DE) | 2007-12-27 | — | — | WO | claimed |
| EP-2766367-B1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for the treatment of viral infections, in particular picornavirus infections | SCANDION ONCOLOGY AS (DK) | 2022-05-18 | — | — | EP | disclosed |
| US-9790225-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2017-10-17 | — | — | US | disclosed |
| US-9790225-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2017-10-17 | — | — | US | disclosed |
| US-9790225-B2 | 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2017-10-17 | — | — | US | disclosed |
| US-8962634-B2 | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2014-10-02 | — | — | US | disclosed |
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2014-10-02 | — | — | US | disclosed |
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | SCANDION ONCOLOGY A/S (DK) | 2014-10-02 | — | — | US | disclosed |
| EP-2766367-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS ANTIVIRAL ACTIVE SUBSTANCES | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053942-A1 | 4-AMINO-3-PHENYLAMINO-6-PHENYLPYRAZOLO[3,4-D] PYRIMIDINE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS ANTIVIRAL ACTIVE SUBSTANCES | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2013-04-18 | — | — | WO | disclosed |
| EP-2049540-B1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2049540-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co.KG (DE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007147401-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO.KG (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296259-A1 | 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and their use as antiviral active substances | POLL, RPP30, EIF2AK2 | ABCG2 1780/4885ALDH1A1 1348/4885LMNA 1817/4885 |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | PNP, TYMP, EIF2AK2 | ABCG2 136/4885ALDH1A1 1623/4885LMNA 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.