⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857777 | 1.00 | — | — | |
| SCHEMBL28659321 | 1.00 | — | — | |
| SCHEMBL6605907 | 0.82 | DPP4 (0.32) | — | |
| SCHEMBL17002637 | 0.80 | DPP4 (0.32) | — | |
| SCHEMBL7453028 | 0.80 | — | — | |
| SCHEMBL96104 | 0.80 | — | — | |
| SCHEMBL4433093 | 0.80 | — | — | |
| SCHEMBL27626884 | 0.78 | GABRA1 (0.31) | — | |
| SCHEMBL27540844 | 0.77 | — | — | |
| SCHEMBL3588998 | 0.77 | TAAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507945-B | Pyrrolo- [2,3 B] pyrazine as SYK inhibitor | 霍夫曼-拉罗奇有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-105289481-A | Solvent oil refined adsorbent and preparation method thereof | SHANDONG CHENG TAI CHEMICAL CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105198691-A | Synthesis method for p-xylene | SHANDONG CHENGTAI CHEMICAL CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-100522359-C | Method for preparing catalyst for methylbenzene shape selective disproportionation reaction to synthesizing para-xylene | CHINA PETROLEUM & CHEMICAL (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-101121140-A | Method for preparing catalyst for methylbenzene shape selective disproportionation reaction to synthesizing para-xylene | CHINA PETROLEUM & CHEMICAL (CN) | 2008-02-13 | — | — | CN | claimed |
| EP-1027052-A1 | NOVEL COMBINATION | AstraZeneca UK Limited (GB) | 2000-08-16 | — | — | EP | claimed |
| US-6063789-A | Aminoisoquinolines and aminotheinopyridine derivatives and their use as anti-inflammatory agents | ASTRA PHARMACEUTICALS, LTD. (GB) | 2000-05-16 | — | — | US | claimed |
| US-6046191-A | PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AN AMIDINE COMPOUND; FOR TREATMENT OF INFLAMMATORY DISORDERS | ASTRA PHARMACEUTICALS LTD. (GB) | 2000-04-04 | — | — | US | claimed |
| WO-1999018960-A1 | NOVEL COMBINATION | ASTRAZENECA UK LIMITED (GB) | 1999-04-22 | — | — | WO | claimed |
| EP-0892784-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Astra Pharmaceuticals Limited (GB) | 1999-01-27 | — | — | EP | claimed |
| WO-1997038977-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-10-23 | — | — | WO | claimed |
| WO-2024092185-A1 | ACYL SULFONAMIDE COMPOUNDS AS INHIBITORS OF POLYOMAVIRUS | VIA NOVA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20230293702-A1 | QUINAZOLINES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2023178130-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| US-10160769-B2 | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-12-25 | — | — | US | disclosed |
| EP-0254032-A2 | Neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0227818-A1 | ANTIGLAUCOMA COMPOSITIONS. | SCHERING CORP (US) | 1987-07-08 | — | — | EP | disclosed |
| WO-1987000055-A1 | ANTIGLAUCOMA COMPOSITIONS | SCHERING CORPORATION (US) | 1987-01-15 | — | — | WO | disclosed |
| US-4389417-A | INDANYLOXYACETIC ACIDS | MERCK & CO., INC. (US) | 1983-06-21 | — | — | US | disclosed |
| US-4098860-A | PRODUCTION OF BIAXIALLY DRAWN FILM OF POLYAMIDE BLEND | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1978-07-04 | — | — | US | disclosed |