Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL836819 | 0.98 | CES1 (0.61) | CES1CA1CA2TDP1TSHR | |
| Oxalic Acid SCHEMBL27286923 | 0.94 | TDP1 (0.60) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL10825957 | 0.91 | MAPK1 (0.76) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL8923535 | 0.85 | MAOB (0.50) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL5099884 | 0.82 | CES1 (0.61) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL8024786 | 0.82 | MAPK1 (0.62) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL10861302 | 0.80 | TDP1 (0.62) | CES1CA1CA2TDP1TSHR | |
| SCHEMBL18124632 | 0.79 | CYP3A4 (0.53) | CES1CA1CA2TSHRALDH1A1 | |
| SCHEMBL222221 | 0.79 | ALDH1A1 (0.74) | TDP1TSHRALDH1A1MAPK1CYP1B1 | |
| SCHEMBL2561308 | 0.79 | MAOB (0.62) | CES1CA1CA2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220290106-A1 | Method for Promoting Cell Proliferation, and Method for Preparing Cell Cluster | OSAKA UNIVERSITY (JP) | 2022-09-15 | — | — | US | claimed |
| EP-3998333-A1 | METHOD FOR PROMOTING CELL PROLIFERATION, AND METHOD FOR PREPARING CELL CLUSTER | Osaka University (JP) | 2022-05-18 | — | — | EP | claimed |
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2022-05-12 | — | — | US | claimed |
| CN-114269332-A | Compositions and methods relating to tethered ethoxydihydroxybutanone derivatives | 芝加哥大学 | 2022-04-01 | — | — | CN | claimed |
| EP-3972576-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | The University of Chicago (US) | 2022-03-30 | — | — | EP | claimed |
| WO-2021006346-A1 | METHOD FOR PROMOTING CELL PROLIFERATION, AND METHOD FOR PREPARING CELL CLUSTER | 国立大学法人大阪大学 | 2021-01-14 | — | — | WO | claimed |
| WO-2020237262-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2020-11-26 | — | — | WO | claimed |
| US-20130189245-A1 | METHOD FOR PRODUCING TOXOIDS USING ALPHA-DICARBONYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2013-07-25 | — | — | US | claimed |
| EP-2593132-A2 | METHOD FOR PRODUCING TOXOIDS USING ALPHA - DICARBONYL COMPOUNDS& xA; | The Secretary of State for Defence (GB) | 2013-05-22 | — | — | EP | claimed |
| CN-103079590-A | Method for producing toxoids using alpha - dicarbonyl compounds | SECR DEFENCE | 2013-05-01 | — | — | CN | claimed |
| WO-2012007728-A2 | TOXOIDING METHOD | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2012-01-19 | — | — | WO | claimed |
| US-20220290106-A1 | Method for Promoting Cell Proliferation, and Method for Preparing Cell Cluster | OSAKA UNIVERSITY (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-3998333-A1 | METHOD FOR PROMOTING CELL PROLIFERATION, AND METHOD FOR PREPARING CELL CLUSTER | Osaka University (JP) | 2022-05-18 | — | — | EP | disclosed |
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2022-05-12 | — | — | US | disclosed |
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2022-05-12 | — | — | US | disclosed |
| EP-0617283-A1 | Method for measuring adenyl group-containing substances | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-5053509-A | Microbiocides; AIDS | LABORATOIRE ROGER BELLON (FR) | 1991-10-01 | — | — | US | disclosed |
| US-4129729-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | KLK3, ANXA6, CKMT1A; CKMT1B | CES1 3018/4885CA1 1090/4885CA2 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.