SCHEMBL360323

SCHEMBL360323

O=Cc1cnc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29102882 0.79
SCHEMBL13574822 0.76
SCHEMBL14676728 0.76
SCHEMBL17099921 0.75 ALDH1A1 (0.48)
SCHEMBL30957 0.73
SCHEMBL27736239 0.73
SCHEMBL8449660 0.73
SCHEMBL13877137 0.73 TDP1 (0.44)
SCHEMBL12151092 0.71
SCHEMBL4984891 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082329-B Pyrazole amide compound containing thiazole ring, and preparation method and application thereof 浙江工业大学 2024-05-28 CN claimed
CN-112684070-B Method for measuring semi-volatile organic compounds in solid waste 山东微谱检测技术有限公司 2024-05-24 CN claimed
CN-116082329-A Pyrazole amide compound containing thiazole ring, and preparation method and application thereof 浙江工业大学 2023-05-09 CN claimed
CN-112684070-A Method for measuring semi-volatile organic compounds in solid waste 山东微谱检测技术有限公司 2021-04-20 CN claimed
CN-109678814-B Method for preparing 2-chloro-1, 3-thiazole-5-formaldehyde 浙江外国语学院 2021-03-23 CN claimed
CN-111978314-A Preparation method of secondary amine compound containing thiazole ring 浙江工业大学 2020-11-24 CN claimed
CN-109678814-A A method of preparing the chloro- 1,3- thiazole -5- formaldehyde of 2- 浙江外国语学院 2019-04-26 CN claimed
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 EP disclosed
US-12404265-B2 Substituted pyridine derivatives as SARM1 inhibitors NURA BIO, INC. (US) 2025-09-02 US disclosed
US-20250243189-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
CN-120192303-A Aromatic heterocycle-containing substituted amide compound and preparation method and application thereof 江西天宇化工有限公司 2025-06-24 CN disclosed
US-20250188094-A1 PYRAZOLE MEMBRANE-ASSOCIATED TYROSINE-AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF INSILICO MEDICINE LTD. (CN) 2025-06-12 US disclosed
WO-2025106482-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-05-22 WO disclosed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed