⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166032 | 0.84 | CA2 (0.32) | — | |
| SCHEMBL3854085 | 0.82 | — | — | |
| SCHEMBL584204 | 0.78 | — | — | |
| SCHEMBL2256073 | 0.75 | — | — | |
| SCHEMBL57483 | 0.73 | — | — | |
| SCHEMBL28005723 | 0.73 | — | — | |
| SCHEMBL584203 | 0.73 | — | — | |
| SCHEMBL20548212 | 0.73 | — | — | |
| SCHEMBL14127424 | 0.73 | — | — | |
| SCHEMBL10277833 | 0.73 | PIK3CD (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234958-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | D. E. SHAW RESEARCH, LLC | 2023-07-27 | — | — | US | disclosed |
| CN-110573505-B | C 5 -anilinoquinazoline compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2023-04-11 | — | — | CN | disclosed |
| WO-2020239656-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF HEPATITIS B | GALAPAGOS NV (BE) | 2020-12-03 | — | — | WO | disclosed |
| EP-1600442-B1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | MSD KK (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-7754743-B2 | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20090018056-A1 | Heteroarylcarbamoylbenzene derivatives | MSD K.K. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-7432287-B2 | Heteroarylcarbamoylbenzene derivative | BANYU PHARMECEUTICAL CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | MSD K.K. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6756195-B2 | GENERATION OF MICROARRAY; GENERATE METAL BINDING LIGAND, INCUBATE WITH METAL, RECOVER MICROARRAY | SYMYX TECHNOLOGIES, INC. | 2004-06-29 | — | — | US | disclosed |
| EP-0983983-A2 | Combinatorial synthesis and analysis of organometallic compounds and catalysts | Symyx Technologies (US/US) (US) | 2000-03-08 | — | — | EP | disclosed |
| US-6030917-A | SYNTHESIZING METAL-BINDING LIGANDS ON SEPARATE REGIONS ON SUBSTRATE; DELIVERING METAL IONS; ACTIVATING METAL-LIGAND COMPOUND WITH ACTIVATOR SELECTED FROM ALKYLATION AGENTS OR IONIZATION AGENTS TO FORM ACTIVATED COMPOUND | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0978499-A2 | Combinatorial synthesis and analysis of organometallic compounds and catalysts | Symyx Technologies (US/US) (US) | 2000-02-09 | — | — | EP | disclosed |
| EP-0923590-A1 | COMBINATORIAL SYNTHESIS AND ANALYSIS OF ORGANOMETALLIC COMPOUNDS AND CATALYSTS | SYMYX TECHNOLOGIES (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998003521-A1 | COMBINATORIAL SYNTHESIS AND ANALYSIS OF ORGANOMETALLIC COMPOUNDS AND CATALYSTS | SYMYX TECHNOLOGIES (US) | 1998-01-29 | — | — | WO | disclosed |
| EP-0504812-B1 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL CO (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5302619-A | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5262441-A | APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0504812-A2 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-3969468-A | 2-Amino-1,2,3,4-tetrahydronaphthalene derivatives | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-07-13 | — | — | US | disclosed |