Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.51 |
| ▸ | SCD | O00767 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602454 | 0.92 | RAF1 (0.47) | SCD5SCDNAMPTABCB1RAF1 | |
| SCHEMBL3600477 | 0.92 | NAMPT (0.51) | SCD5SCDNAMPTABCB1ESR2 | |
| SCHEMBL3605783 | 0.91 | NAMPT (0.56) | SCD5SCDNAMPT | |
| SCHEMBL3615748 | 0.90 | SCD (0.53) | SCD5SCDNAMPTALDH1A1ESR2 | |
| SCHEMBL3605404 | 0.89 | NAMPT (0.63) | SCD5SCDNAMPTABCB1ALDH1A1 | |
| SCHEMBL3602755 | 0.89 | SCD (0.51) | SCD5SCDNAMPTABCB1ALDH1A1 | |
| SCHEMBL3601422 | 0.88 | RAF1 (0.43) | SCD5SCDNAMPTRAF1BRAF | |
| SCHEMBL3616386 | 0.87 | ITK (0.51) | SCD5SCDNAMPTALDH1A1ESR2 | |
| SCHEMBL3598199 | 0.87 | NAMPT (0.56) | SCD5SCDNAMPTALDH1A1ESR2 | |
| SCHEMBL3603596 | 0.86 | SCD (0.53) | SCD5SCDNAMPTALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SCD5 4/4885SCD 2/4885NAMPT 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.