Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316351 | 0.84 | ALDH1A1 (0.51) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13166438 | 0.84 | ALDH1A1 (0.51) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3342656 | 0.82 | PREP (0.57) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25186706 | 0.82 | PREP (0.57) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3336958 | 0.82 | PREP (0.57) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25766824 | 0.80 | PREP (0.44) | PREPSMN1; SMN2RAB9ADRD2DRD3 | |
| SCHEMBL13316374 | 0.80 | PREP (0.50) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13349564 | 0.80 | PREP (0.50) | PREPALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4941260 | 0.80 | PREP (0.44) | PREPALDH1A1SMN1; SMN2RAB9ADRD2 | |
| SCHEMBL31037738 | 0.80 | PREP (0.52) | PREPALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683056-B2 | Pyridine derivatives and their use in the treatment of psychotic disorders | GLAXOSMITHKLINE LLC (US) | 2010-03-23 | — | — | US | disclosed |