Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614065 | 0.84 | ERN1 (0.51) | ERN1ARCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3609274 | 0.84 | ERN1 (0.52) | ERN1ALDH1A1MAPT | |
| SCHEMBL3613315 | 0.84 | ERN1 (0.56) | ERN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3614027 | 0.79 | ERN1 (0.55) | ERN1CYP3A4ALDH1A1MAPT | |
| SCHEMBL3604651 | 0.78 | ERN1 (0.43) | ERN1ARNLRP3ALDH1A1 | |
| SCHEMBL6896479 | 0.77 | FGFR1 (0.47) | GRM5NLRP3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3618296 | 0.75 | ERN1 (0.56) | ERN1CYP3A4ALDH1A1MAPTTHRB | |
| SCHEMBL453334 | 0.75 | ALDH1A1 (0.45) | ERN1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3606927 | 0.74 | ERN1 (0.45) | ERN1ALDH1A1 | |
| SCHEMBL3611783 | 0.74 | ERN1 (0.48) | ERN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | claimed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | claimed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | claimed |
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | disclosed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | PDLIM5, PSD, PDCD6IP | ERN1 2349/4885AR 4715/4885GRM5 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.