SCHEMBL3604154

SCHEMBL3604154

Cc1c(Br)c2c(c(C)c1NC(=O)CC(C)(C)C)CC(C)(C)O2

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 12/20 0.40
EZH2 Q15910 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KCNQ3 O43525 8/20 0.33
MAOB P27338 1/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3597158 0.83 KCNQ2 (0.39) KCNQ2EZH2L3MBTL1MEN1KMT2A
SCHEMBL4082475 0.83 EZH2 (0.37) EZH2MEN1KMT2AALDH1A1
SCHEMBL3601737 0.78 KCNQ2 (0.38) KCNQ2L3MBTL1MEN1KMT2AMAOB
SCHEMBL3599822 0.77 KCNQ2 (0.37) KCNQ2L3MBTL1MEN1KMT2AKCNQ3
SCHEMBL3597526 0.77 KCNQ2 (0.36) KCNQ2L3MBTL1MEN1KMT2AMAOB
SCHEMBL3589337 0.77 KCNQ2 (0.39) KCNQ2EZH2L3MBTL1MEN1KMT2A
SCHEMBL3590506 0.76 KCNQ2 (0.36) KCNQ2L3MBTL1MEN1KMT2AMAOB
SCHEMBL3607325 0.76 KCNQ2 (0.36) KCNQ2L3MBTL1MEN1KMT2AMAOB
SCHEMBL3596027 0.76 KCNQ2 (0.51) KCNQ2L3MBTL1MAOB
SCHEMBL3599090 0.75 KCNQ2 (0.37) KCNQ2L3MBTL1MEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024024692-A1 ACTIVE LIGHT-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMATION METHOD, AND ELECTRONIC DEVICE MANUFACTURING METHOD 富士フイルム株式会社 2024-02-01 WO claimed
US-10286377-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2019-05-14 US claimed
US-9339782-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2016-05-17 US claimed
US-7718579-B2 Electrochemical deblocking using a hydrazine derivative COMBIMATRIX CORPORATION (US) 2010-05-18 US claimed
US-7541314-B2 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION (US) 2009-06-02 US claimed
EP-1945750-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCINATE LINKER Combimatrix Corporation (US) 2008-07-23 EP claimed
US-20080125327-A1 Bonding amino moieties to solid surface with reactive hydroxyl groups, bonding succinate moieties to the amine groups through amide bonds to form cleavable linkers attached to the solid surface, bonding a succinate group, a sugar group and a base group, synthesizing oligonucleotides CUSTOMARRAY, INC. 2008-05-29 US claimed
US-20080105541-A1 Electrode Array Device Having An Adsorbed Porous Reaction Layer STRATHMANN MICHAEL P 2008-05-08 US claimed
WO-2007100793-A2 MICROARRAY HAVING A BASE CLEAVABLE SULFONYL LINKER COMBIMATRIX CORPORATION (US) 2007-09-07 WO claimed
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION 2007-08-30 US claimed
US-20060105355-A1 Electrode array device having an adsorbed porous reaction layer having a linker moiety KARL MAURER 2006-05-18 US claimed
US-20060102471-A1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. 2006-05-18 US claimed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 WO claimed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 US claimed
US-5977117-A Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 1999-11-02 US claimed
EP-0876364-A2 SUBSTITUTED PHENYL COMPOUNDS AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1998-11-11 EP claimed
WO-1997025321-A2 SUBSTITUTED PHENYL COMPOUNDS AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-07-17 WO claimed
EP-0131161-B1 HEAT-DEVELOPABLE COLOR PHOTOSENSITIVE ELEMENT KONICA CORPORATION (JP) 1988-11-02 EP claimed
US-4770989-A USING A THERMAL SOLVENT AND GELATIN/POLYVINYPYRROLIDONE POLYMER MIXTURE; DIFFUSION TRANSFER QUALITY IMAGE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US claimed
EP-0131161-A2 Heat-developable color photosensitive element KONICA CORPORATION (JP) 1985-01-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker DPP8, DPP4, SI KCNQ2 3305/4885EZH2 890/4885L3MBTL1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.