SCHEMBL3604186

SCHEMBL3604186

CC(=O)OOC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12273897 0.83 ALDH1A1 (0.32)
SCHEMBL24499 0.79
SCHEMBL18403873 0.77
Methane SCHEMBL25208404 0.77 ALDH1A1 (0.41)
Hydrogen Peroxide SCHEMBL6657321 0.77 ALDH1A1 (0.46)
SCHEMBL11576971 0.73
Tert-Butyl Hydroperoxide SCHEMBL2494129 0.72 ALDH1A1 (0.47)
SCHEMBL83061 0.72 GAA (0.41)
Benzene SCHEMBL21084039 0.72 ALDH1A1 (0.54)
Ethaneperoxoic Acid SCHEMBL8898688 0.72 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000034288-A1 PROCESS FOR REMOVAL OF CYANIDE FROM REACTIONS PRODUCING 1,3 DIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-15 WO claimed
CN-101168529-B Fipronil, ethiprole and synthesizing method for derivative thereof UNIV WENZHOU 2011-03-23 CN disclosed
US-20100016285-A1 HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128157-A1 HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2009-12-02 EP disclosed
CN-101168529-A Fipronil, ethiprole and synthesizing method for derivative thereof UNIV WENZHOU (CN) 2008-04-30 CN disclosed
EP-0799056-B1 USE OF A NK-1 RECEPTOR ANTAGONIST AND AN OPIOID ANALGESIC MERCK SHARP & DOHME (GB) 2002-03-27 EP disclosed
CN-1075812-C Prodrugs of morpholine tachykinin receptor antagonists MERCK & CO INC (US) 2001-12-05 CN disclosed
US-6180624-B1 BY ADMINISTERING A COMBINATION OF A MORPHOLINE OR THIOMORPHOLINE TACHYKININ ANTAGONIST AND AN OPIOID ANALGESIC MERCK SHARP & DOHME LIMITED (GB) 2001-01-30 US disclosed
US-6140324-A ADMINISTERING TACHYKININ ANTAGONIST AND MUSCARINIC ANTAGONIST AND/OR ANTIHISTAMINE, SUCH THAT THEY GIVE EFFECTIVE RELIEF FROM MOTION SICKNESS MERCK SHARP & DOHME LTD. (GB) 2000-10-31 US disclosed
WO-2000034288-A1 PROCESS FOR REMOVAL OF CYANIDE FROM REACTIONS PRODUCING 1,3 DIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-15 WO disclosed
WO-1995023798-A1 PRODRUGS OF MORPHOLINE TACHYKININ RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-09-08 WO disclosed
CN-1028475-C Pyrrole insecticides RHONE POULENC AGROCHIMIE (FR) 1995-05-24 CN disclosed
CN-1043500-A PYRROLE INSECTICIDES RHONE POULENC AGROCHIMIE (FR) 1990-07-04 CN disclosed
EP-0372982-A2 Pyrrole insecticides RHONE-POULENC AGROCHIMIE (FR) 1990-06-13 EP disclosed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed
US-4528332-A Epoxy compounds, process for the preparation thereof and resist materials comprising thereof ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-07-09 US disclosed
EP-0012760-B1 PHARMACEUTICALLY ACTIVE 6,9-THIAPROSTACYCLIN ANALOGS AND DERIVATIVES THEREOF Research Corporation (US) 1983-10-19 EP disclosed
US-4291166-A ANTICOAGULANTS RESEARCH CORPORATION (US) 1981-09-22 US disclosed
EP-0012760-A1 PHARMACEUTICALLY ACTIVE 6,9-THIAPROSTACYCLIN ANALOGS AND DERIVATIVES THEREOF. RESEARCH CORP (US) 1980-07-09 EP disclosed
WO-1979000744-A1 PHARMACEUTICALLY ACTIVE 6,9-THIAPROSTACYCLIN ANALOGS AND DERIVATIVES THEREOF RESEARCH CORP (US) 1979-10-04 WO disclosed