Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.53 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357690 | 1.00 | SSTR1 (0.53) | SSTR1SSTR4DRD4SIGMAR1HPGD | |
| SCHEMBL14392388 | 1.00 | SSTR1 (0.53) | SSTR1SSTR4DRD4SIGMAR1HPGD | |
| SCHEMBL1908903 | 0.88 | SSTR1 (0.67) | SSTR1SSTR4DRD4HPGDEPHX1 | |
| SCHEMBL13242298 | 0.86 | DRD4 (0.66) | SSTR1SSTR4DRD4HPGDEPHX1 | |
| SCHEMBL14263126 | 0.81 | SSTR1 (0.57) | SSTR1SSTR4DRD4HPGDEPHX1 | |
| SCHEMBL14263134 | 0.81 | DRD4 (0.55) | SSTR1SSTR4DRD4HPGDEPHX1 | |
| SCHEMBL359497 | 0.80 | ALDH1A1 (0.51) | DRD4KMT2ANAMPT | |
| SCHEMBL4981951 | 0.80 | MCHR1 (0.56) | SSTR4DRD4SIGMAR1HPGDEPHX1 | |
| SCHEMBL4981612 | 0.80 | DRD4 (0.57) | DRD4SIGMAR1HPGDEPHX1MCHR1 | |
| SCHEMBL1912322 | 0.79 | EPHX2 (0.50) | EPHX2MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |