Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.59 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593647 | 0.86 | BRD4 (0.66) | BRD4CREBBPBRD2 | |
| SCHEMBL13090753 | 0.81 | BRD4 (0.61) | BRD4CREBBPBRD2CRBNTRPV1 | |
| SCHEMBL4123040 | 0.79 | BRD4 (0.76) | BRD4CREBBPBRD2CRBNTRPV1 | |
| SCHEMBL3599751 | 0.79 | BRD4 (0.59) | BRD4CREBBPBRD2CRBNTRPV1 | |
| SCHEMBL13545265 | 0.77 | BRD4 (0.56) | BRD4CREBBPTRPV1 | |
| SCHEMBL3600319 | 0.76 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL3584898 | 0.76 | ALDH1A1 (0.39) | BRD4CREBBP | |
| SCHEMBL4123663 | 0.76 | BRD4 (0.54) | BRD4CREBBPTRPV1 | |
| SCHEMBL31490089 | 0.76 | BRD4 (0.54) | BRD4CREBBPTRPV1 | |
| SCHEMBL3604229 | 0.74 | BRD4 (0.53) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | BRD4 706/4885CREBBP 2015/4885BRD2 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.