Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 17/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 14/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3614515 | 0.93 | KCNH2 (0.36) | KCNH2CYP19A1 | |
| Trifluoroacetic Acid SCHEMBL3614777 | 0.89 | KCNH2 (0.35) | DPP4DPP7DPP8DPP9KCNH2 | |
| Trifluoroacetic Acid SCHEMBL3620786 | 0.89 | KCNH2 (0.33) | DPP4DPP7DPP8DPP9KCNH2 | |
| Trifluoroacetic Acid SCHEMBL3611349 | 0.86 | DPP4 (0.37) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL3604469 | 0.85 | KCNH2 (0.33) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL3618485 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3617297 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3618356 | 0.82 | KCNH2 (0.35) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3607827 | 0.81 | KCNH2 (0.38) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3611488 | 0.81 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | NRDC, NDC1, NANS | DPP4 1065/4885DPP7 1321/4885DPP8 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.