Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3620786 | 0.94 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3615901 | 0.92 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL3617780 | 0.87 | KCNH2 (0.37) | KCNH2TOP2AMTOR | |
| Hydrochloric Acid SCHEMBL3614515 | 0.86 | KCNH2 (0.36) | KCNH2TOP2AMTOR | |
| SCHEMBL3610660 | 0.85 | KCNH2 (0.34) | KCNH2TOP2A | |
| SCHEMBL3620789 | 0.84 | KCNH2 (0.32) | KCNH2 | |
| Trifluoroacetic Acid SCHEMBL3604465 | 0.82 | DPP4 (0.35) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3611488 | 0.82 | KCNH2 (0.38) | KCNH2TOP2AMTOR | |
| Hydrochloric Acid SCHEMBL3607827 | 0.82 | KCNH2 (0.38) | KCNH2TOP2AMTOR | |
| SCHEMBL3618485 | 0.82 | KCNH2 (0.36) | KCNH2TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | NRDC, NDC1, NANS | KCNH2 2914/4885TOP2A 78/4885MTOR 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.