Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593053 | 0.83 | AR (0.53) | ARDPP4RPS6KB1AKT1 | |
| SCHEMBL4880027 | 0.79 | AR (0.53) | ARDPP4RPS6KB1AKT1 | |
| SCHEMBL4723950 | 0.79 | AR (0.48) | ARDPP4 | |
| SCHEMBL4871504 | 0.79 | AR (0.50) | AR | |
| SCHEMBL27714512 | 0.78 | AR (0.56) | ARRPS6KB1AKT1 | |
| SCHEMBL3599646 | 0.78 | AR (0.62) | AR | |
| SCHEMBL3615730 | 0.78 | AR (0.62) | AR | |
| SCHEMBL3610108 | 0.78 | AR (0.62) | AR | |
| Hydrochloric Acid SCHEMBL4881079 | 0.77 | AR (0.55) | ARRPS6KB1AKT1 | |
| Hydrochloric Acid SCHEMBL3604641 | 0.77 | AR (0.60) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |
| EP-1553074-A1 | FUSED BENZENE DERIVATIVE AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-07-13 | — | — | EP | disclosed |