SCHEMBL4723950

SCHEMBL4723950

CS(=O)(=O)N(CC1CCCN(c2ccc(C#N)c3ccccc23)C1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 15/20 0.48
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4235271 0.89 AR (0.43) AR
SCHEMBL4235266 0.89 AR (0.45) ARDPP4
SCHEMBL3593053 0.81 AR (0.53) ARDPP4
Hydrochloric Acid SCHEMBL4880006 0.80 AR (0.54) AR
SCHEMBL3604536 0.79 AR (0.47) ARDPP4
SCHEMBL3599646 0.79 AR (0.62) AR
SCHEMBL3615730 0.79 AR (0.62) AR
SCHEMBL3610108 0.79 AR (0.62) AR
SCHEMBL4880027 0.79 AR (0.53) ARDPP4
Hydrochloric Acid SCHEMBL3615726 0.78 AR (0.60) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987827-A1 NOVEL PHARMACEUTICAL Takeda Pharmaceutical Company Limited (JP) 2008-11-05 EP disclosed