Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13142298 | 1.00 | KCNK3 (0.43) | KCNK3KCNK9KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL3605618 | 0.81 | KMT2A (0.36) | KMT2AUSP2SMN1; SMN2PIK3CAUSP30 | |
| SCHEMBL16094599 | 0.79 | PIK3CD (0.44) | KMT2AUSP2SMN1; SMN2PIK3CAUSP30 | |
| SCHEMBL13119769 | 0.78 | SMN1; SMN2 (0.43) | KMT2AUSP2SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL3610408 | 0.78 | RECQL (0.47) | KMT2AUSP2SMN1; SMN2MAPTGPR119 | |
| SCHEMBL16094656 | 0.78 | RAF1 (0.44) | KMT2AUSP2SMN1; SMN2PIK3CAUSP30 | |
| SCHEMBL1497347 | 0.77 | TBK1 (0.49) | USP2SMN1; SMN2PIK3CAGPR119TBK1 | |
| SCHEMBL3997637 | 0.76 | PIK3CA (0.53) | KMT2AUSP2SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL18153347 | 0.76 | PIK3CA (0.53) | KMT2AUSP2SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL29434915 | 0.76 | PIK3CA (0.53) | KMT2AUSP2SMN1; SMN2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256143-A1 | PHARMACEUTICAL COMPOUNDS | BAKER STEWART JAMES | 2010-10-07 | — | — | US | disclosed |
| US-20100256143-A1 | PHARMACEUTICAL COMPOUNDS | BAKER STEWART JAMES | 2010-10-07 | — | — | US | disclosed |
| WO-2008125833-A1 | PHARMACEUTICAL COMPOUNDS | PIRAMED LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256143-A1 | PHARMACEUTICAL COMPOUNDS | PIK3CA, PIK3CD, JAK2 | KCNK3 1515/4885KCNK9 1571/4885KMT2A 3423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.