⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327444 | 0.83 | DYRK1A (0.32) | — | |
| SCHEMBL16005008 | 0.75 | NEK1 (0.30) | — | |
| SCHEMBL288409 | 0.74 | PARP15 (0.34) | — | |
| SCHEMBL22122313 | 0.74 | IDO1 (0.33) | — | |
| SCHEMBL21625566 | 0.74 | CYP1A2 (0.33) | — | |
| SCHEMBL288408 | 0.74 | — | — | |
| SCHEMBL911446 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL21625563 | 0.71 | — | — | |
| SCHEMBL17022644 | 0.70 | DYRK1A (0.31) | — | |
| SCHEMBL3608839 | 0.69 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |
| EP-2850086-B1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-07-05 | — | — | EP | disclosed |
| EP-2850086-B1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20200256798-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2020-08-13 | — | — | US | disclosed |
| US-10458915-B2 | Heteroarylcyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| EP-2850086-A1 | HETEROARYLCYANINE DYES | Pacific Biosciences Of California, Inc. (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-20140080127-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140005404-A1 | Heteroarylcyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-01-02 | — | — | US | disclosed |
| WO-2013173844-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-11-21 | — | — | WO | disclosed |
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20060106067-A1 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-18 | — | — | US | disclosed |
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |
| EP-1553074-A1 | FUSED BENZENE DERIVATIVE AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |