Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800276 | 0.84 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL4598743 | 0.84 | SMN1; SMN2 (0.68) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL3658275 | 0.84 | FLT1 (0.50) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL582402 | 0.84 | TMEM97 (0.61) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL1420957 | 0.82 | HTT (0.57) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL27452028 | 0.82 | HTT (0.57) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL28022560 | 0.81 | HTT (0.53) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL359164 | 0.79 | HTT (0.54) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL4495229 | 0.79 | TSHR (0.61) | HTTTSHRSMN1; SMN2HPGDNPC1 | |
| SCHEMBL4768144 | 0.79 | HDAC3 (0.71) | HTTTSHRSMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980892-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2015-03-17 | — | — | US | disclosed |
| EP-2411384-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-30 | — | — | EP | disclosed |
| EP-2411384-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-02-01 | — | — | EP | disclosed |
| US-20120015946-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2010108733-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015946-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, C1R | HTT 3169/4885TSHR 1739/4885SMN1; SMN2 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.