SCHEMBL360758

SCHEMBL360758

O=Nc1cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.72
KMT2A Q03164 11/20 0.72
CYP3A4 P08684 10/20 0.72
KDM4E B2RXH2 9/20 0.72
CYP2C9 P11712 8/20 0.72
CYP1A2 P05177 8/20 0.72
MAPT P10636 8/20 0.72
HSD17B10 Q99714 8/20 0.72
CYP1A1 P04798 7/20 0.72
CYP1B1 Q16678 7/20 0.72
ABCB1 P08183 6/20 0.72
FTO Q9C0B1 6/20 0.72
XDH P47989 6/20 0.72
CYP2D6 P10635 6/20 0.72
CYP2C19 P33261 5/20 0.72
ALOX15 P16050 5/20 0.72
TP53 P04637 5/20 0.72
ALDH1A1 P00352 5/20 0.72
HPGD P15428 5/20 0.72
APP P05067 5/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25761542 0.88 MEN1 (0.59) MEN1KMT2ACYP3A4KDM4ECYP2C9
SCHEMBL19587031 0.88 ABCB1 (0.79) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL18817 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL30655455 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL1259228 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL29378805 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL31577746 0.83 MEN1 (0.97) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL31256029 0.83 MEN1 (0.97) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL31749037 0.83 MEN1 (0.97) MEN1KMT2ACYP3A4KDM4ECYP2C9
Kaempferol SCHEMBL17237761 0.83 MEN1 (0.97) MEN1KMT2ACYP3A4KDM4ECYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622632-B1 JUCARA AND ACAI FRUIT-BASED DIETARY SUPPLEMENTS K2A LLC (US) 2012-03-14 EP disclosed