Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 3/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | UBA1 | P22314 | 1/20 | 0.31 |
| ▸ | UBE2E1 | P51965 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MARS1 | P56192 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3607999 | 0.83 | DPP4 (0.41) | DPP4DPP7EGLN2KCNH2ALPL | |
| SCHEMBL3602861 | 0.80 | DPP4 (0.34) | DPP4DPP7EGLN2KCNH2CNR1 | |
| SCHEMBL3605363 | 0.78 | DPP4 (0.35) | DPP4DPP7EGLN2CNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL3607995 | 0.73 | DPP4 (0.45) | DPP4DPP7EGLN2KCNH2ALPL | |
| Trifluoroacetic Acid SCHEMBL3605360 | 0.72 | DPP4 (0.38) | DPP4DPP7EGLN2KCNH2ALPL | |
| Trifluoroacetic Acid SCHEMBL3602860 | 0.71 | DPP4 (0.38) | DPP4DPP7EGLN2KCNH2CNR1 | |
| Trifluoroacetic Acid SCHEMBL9102535 | 0.70 | DPP4 (0.35) | DPP4DPP7KCNH2ALPL | |
| SCHEMBL3604219 | 0.68 | EGLN2 (0.49) | DPP4EGLN2ALPLSLC2A1HSP90AA1 | |
| SCHEMBL3599775 | 0.68 | EGLN2 (0.51) | DPP4EGLN2HSP90AA1HSP90AB1 | |
| SCHEMBL4555435 | 0.67 | GSK3B (0.39) | DPP4EGLN2KCNH2ALPLCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051323-B2 | Substituted imidazopyrimidines and triazolopyrimidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20130040946-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| US-8273752-B2 | Substituted imidazopyrimidines and triazolopyrimidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20100113441-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113441-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | TYMP, DPYD, THPO | DPP4 436/4885DPP7 1082/4885EGLN2 1710/4885 |
| US-20130040946-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | THPO, TYMP, TPMT | DPP4 497/4885DPP7 1030/4885EGLN2 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.