Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3607999 | 0.85 | DPP4 (0.41) | DPP4DPP7KCNH2ALPL | |
| SCHEMBL4554539 | 0.76 | MAP4K2 (0.38) | DPP4MAP4K2ALPL | |
| SCHEMBL10270527 | 0.76 | DPP4 (0.43) | DPP4MAP4K2ALPL | |
| Trifluoroacetic Acid SCHEMBL3605360 | 0.75 | DPP4 (0.38) | DPP4DPP7KCNH2MAP4K2ALPL | |
| SCHEMBL3603724 | 0.74 | ALPL (0.41) | DPP4MAP4K2ALPL | |
| SCHEMBL3605363 | 0.73 | DPP4 (0.35) | DPP4DPP7MAP4K2ALPL | |
| Trifluoroacetic Acid SCHEMBL3607995 | 0.71 | DPP4 (0.45) | DPP4DPP7KCNH2ALPL | |
| SCHEMBL10269893 | 0.71 | PCSK9 (0.39) | MAP4K2ALPL | |
| SCHEMBL3608002 | 0.70 | DPP4 (0.34) | DPP4DPP7KCNH2ALPL | |
| Trifluoroacetic Acid SCHEMBL3602860 | 0.68 | DPP4 (0.38) | DPP4DPP7KCNH2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137188-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Pharma AG (DE) | 2012-06-06 | — | — | EP | disclosed |