SCHEMBL3608058

SCHEMBL3608058

CCCCCCCCc1ccc(C)c(Cc2ccccc2)c1CCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.43
LIPG Q9Y5X9 1/20 0.42
DNM1 Q05193 2/20 0.41
TLR8 Q9NR97 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TP53 P04637 2/20 0.41
TYR P14679 2/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 3/20 0.40
SIGMAR1 Q99720 1/20 0.39
CYP3A4 P08684 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151817 0.97 KCNH2 (0.43) KCNH2LIPGDNM1TLR8MEN1
SCHEMBL29144403 0.88 LIPG (0.46) KCNH2LIPGTLR8
SCHEMBL10359974 0.88 KCNH2 (0.43) KCNH2LIPGDNM1TLR8MEN1
SCHEMBL8101482 0.83 LIPG (0.51) KCNH2LIPGTLR8
SCHEMBL8096674 0.83 LIPG (0.51) KCNH2LIPGTLR8
SCHEMBL8095441 0.83 LIPG (0.51) KCNH2LIPGTLR8
SCHEMBL11332831 0.83 TYR (0.50) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL7773731 0.83 TYR (0.50) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL8099594 0.82 LIPG (0.49) KCNH2LIPGTLR8SIGMAR1ALOX5
Trimethylammonium SCHEMBL11230357 0.81 KCNH2 (0.41) KCNH2DNM1TLR8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1682324-B1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE PRYSMIAN SPA (IT) 2016-08-10 EP disclosed
US-7807091-B2 Method and plant for the introduction of a liquid into a molten mass under pressure PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2010-10-05 US disclosed
CN-100544932-C Insert the liquid into the method and apparatus of the fused materials under the pressure PRYSMIAN CAVI SISTEMI ENERGIA (IT) 2009-09-30 CN disclosed
US-20070248748-A1 Method and Plant for the Introduction of a Liquid Into a Molten Mass Under Pressure PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2007-10-25 US disclosed
CN-1886245-A Method and device for introducing a liquid into a molten mass under pressure PRYSMIAN CAVI SISTEMI ENERGIA (IT) 2006-12-27 CN disclosed
EP-1682324-A1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE Prysmian Cavi e Sistemi Energia S.r.l. (IT) 2006-07-26 EP disclosed
WO-2005042226-A1 METHOD AND PLANT FOR THE INTRODUCTION OF A LIQUID INTO A MOLTEN MASS UNDER PRESSURE PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2005-05-12 WO disclosed