Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 18/20 | 0.44 |
| ▸ | AKT2 | P31751 | 13/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361402 | 0.88 | AKT1 (0.51) | AKT1AKT2TACR3 | |
| SCHEMBL538068 | 0.87 | AKT1 (0.41) | AKT1AKT2TACR3 | |
| SCHEMBL538868 | 0.82 | AKT1 (0.64) | AKT1AKT2 | |
| SCHEMBL363205 | 0.80 | AKT1 (0.43) | AKT1AKT2TACR3 | |
| SCHEMBL530117 | 0.77 | AKT1 (0.69) | AKT1AKT2 | |
| SCHEMBL866493 | 0.75 | AKT1 (0.52) | AKT1AKT2TACR3 | |
| SCHEMBL360660 | 0.75 | AKT1 (0.46) | AKT1AKT2 | |
| SCHEMBL538629 | 0.75 | AKT1 (0.47) | AKT1AKT2TACR3 | |
| SCHEMBL868279 | 0.75 | AKT1 (0.46) | AKT1AKT2 | |
| SCHEMBL2979576 | 0.74 | AKT1 (0.47) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593458-A1 | BICYCLIC PYRIMIDINES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007416-A1 | BICYCLIC PYRIMIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |