Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625497 | 0.90 | CYP4F2 (0.54) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB | |
| SCHEMBL29923060 | 0.86 | CYP4F2 (0.53) | CYP4F2CYP4A11BAZ2BBAZ2ACA1 | |
| SCHEMBL6732086 | 0.86 | CYP4F2 (0.53) | CYP4F2CYP4A11BAZ2BBAZ2ACA1 | |
| SCHEMBL5088670 | 0.85 | CYP4F2 (0.56) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB | |
| SCHEMBL8137124 | 0.84 | TSHR (0.50) | CYP4F2CYP4A11MAOBCA1CA2 | |
| SCHEMBL18703677 | 0.83 | GAA (0.46) | CA1CA2CA12CA9CA7 | |
| SCHEMBL34463695 | 0.83 | TSHR (0.50) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB | |
| SCHEMBL31497641 | 0.82 | CA1 (0.53) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB | |
| SCHEMBL8712980 | 0.82 | CA1 (0.53) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB | |
| SCHEMBL1560843 | 0.81 | CYP4F2 (0.56) | CYP4F2CYP4A11BAZ2BBAZ2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105673-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100105673-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100105673-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2102180-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071359-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071359-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105673-A1 | SUBSTITUTED AMINOFURANONES AND THEIR USE | FANCF, TPMT, AAAS | CYP4F2 101/4885CYP4A11 1545/4885BAZ2B 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.