SCHEMBL6732086

SCHEMBL6732086

CCOC(=O)c1cc(Cl)c(Cl)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
BAZ2B Q9UIF8 1/20 0.53
BAZ2A Q9UIF9 1/20 0.53
TSHR P16473 1/20 0.52
CA1 P00915 6/20 0.48
CA2 P00918 6/20 0.48
CA12 O43570 5/20 0.48
CA9 Q16790 5/20 0.48
CA7 P43166 4/20 0.47
CA14 Q9ULX7 4/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPK1 P28482 1/20 0.45
KDM4E B2RXH2 1/20 0.45
KMT2A Q03164 1/20 0.45
METTL3 Q86U44 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29923060 1.00 CYP4F2 (0.53) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL236240 0.90 CYP4F2 (0.57) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL18703599 0.87 CA1 (0.51) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL3608649 0.86 CYP4F2 (0.51) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL11725048 0.86 ALDH1A1 (0.51) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL16302043 0.86 TSHR (0.61) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL4625705 0.85 CYP4F2 (0.53) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL15920586 0.83 CYP4F2 (0.51) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL10656841 0.83 CA1 (0.59) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL10431608 0.81 CYP4F2 (0.50) CYP4F2CYP4A11BAZ2BBAZ2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028596-B Method for preparing topramezone intermediate 帕潘纳(北京)科技有限公司 2024-06-07 CN disclosed
CN-115028596-A Process for preparing topramezone intermediates 帕潘纳(北京)科技有限公司 2022-09-09 CN disclosed
US-20040162221-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2004-08-19 US disclosed
US-6677460-B1 Aromatic carboxylic acid bicyclic sulfur compounds IDEMITSU KOSAN COMPANY, LIMITED (JP) 2004-01-13 US disclosed
US-20030236421-A1 AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS IDEMITSU KOSAN COMPANY, LIMITED (JP) 2003-12-25 US disclosed
US-20030220199-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2003-11-27 US disclosed
US-20020133024-A1 Aromatic carboxylic acid bicyclic sulfur compounds IDEMITSU KOSAN COMPANY, LIMITED (JP) 2002-09-19 US disclosed
US-20020115568-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO. LTD. (JP) 2002-08-22 US disclosed
US-20020016262-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2002-02-07 US disclosed
US-20010051733-A1 Aromatic carboxylic acid bicyclic sulfur compounds IDEMITSU KOSAN COMPANY, LIMITED (JP) 2001-12-13 US disclosed
US-6159904-A Pyrazole derivatives IDEMITSU KOSAN CO., LTD. (JP) 2000-12-12 US disclosed
US-6136755-A HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
US-6103668-A Pyrazole derivatives IDEMITSU KOSAN CO., LTD. (JP) 2000-08-15 US disclosed
US-6063936-A CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE IDEMITSU KOSAN CO., LTD. (JP) 2000-05-16 US disclosed
EP-0970956-A1 PYRAZOLE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-01-12 EP disclosed
US-5767289-A HERBICIDE INTERMEDIATES IDEMITSU KOSAN COMPANY, LIMITED (JP) 1998-06-16 US disclosed
EP-0810226-A1 PYRAZOLE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-03 EP disclosed
US-5607898-A HERBICIDES IDEMITSU KOSAN COMPANY, LTD. (JP) 1997-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115568-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 CYP4F2 47/4885CYP4A11 165/4885BAZ2B 1505/4885
US-20030236421-A1 AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS XDH, SULT2A1, NAT1 CYP4F2 368/4885CYP4A11 738/4885BAZ2B 1721/4885
US-20010051733-A1 Aromatic carboxylic acid bicyclic sulfur compounds XDH, SULT2A1, NAT1 CYP4F2 368/4885CYP4A11 738/4885BAZ2B 1721/4885
US-20020016262-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 CYP4F2 47/4885CYP4A11 165/4885BAZ2B 1505/4885
US-20040162221-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 CYP4F2 47/4885CYP4A11 165/4885BAZ2B 1505/4885
US-20030220199-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 CYP4F2 47/4885CYP4A11 165/4885BAZ2B 1505/4885
US-20020133024-A1 Aromatic carboxylic acid bicyclic sulfur compounds XDH, SULT2A1, NAT1 CYP4F2 368/4885CYP4A11 738/4885BAZ2B 1721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.